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Cy7 azide (non-sulfonated)

 
Catalog No.
A8115
用于点击化学,标记炔烃修饰的寡核苷酸
组合的产品项目
规格价格库存 数量
5mg
¥ 10,963.00
Ship with 10-15 days
25mg
¥ 32,175.00
Ship with 10-15 days

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A

背景

Cy7 azide is a labeling reagent that ready for the use in Click Chemistry labeling. This labeling dye is a near-infrared dye which has low aqueous solubility. For biomolecule labeling, the labeling reagent has low aqueous solubility, using of organic co-solvent to dissolve this molecules is necessary for efficient reaction. First, Cyanine dye should be dissolved in organic solvent and then added to a solution of biomolecule in appropriate aqueous buffer. This product can be used for the incorporation of Cy7 azide into various biomolecules and post-synthetic modification of oligonucleotides is also available.

PEG-b-PPLG-Cy7 was conjugated by Cy7 azid and the polymer of PEG-b-PPLG. In blank micelles, it was used to probe the association of unimers [1].

Reference:
[1] Morton, S. W.; Zhao, X.; Quadir, M.A.; Hammond, P.T. FRET-enabled biological characterization of polymeric micelles. Biomaterials,2014, 35(11), 3489-3496.

化学属性

Storage24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
M.Wt667.33
FormulaC40H51ClN6O
Solubilitysoluble in organic solvents (DMSO, DMF, dichloromethane), low solubility in water
Chemical NameN-(3-azidopropyl)-6-[(2E)-3,3-dimethyl-2-[(2E)-2-[3-[(E)-2-(1,3,3-trimethylindol-1-ium-2-yl)ethenyl]cyclohex-2-en-1-ylidene]ethylidene]indol-1-yl]hexanamide
SDFDownload SDF
Canonical SMILESCC1(C2=CC=CC=C2[N+](=C1C=CC3=CC(=CC=C4C(C5=CC=CC=C5N4CCCCCC(=O)NCCCN=[N+]=[N-])(C)C)CCC3)C)C
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Spectral properties

最大激发光波 (nm) 750 最大发射光波 (nm) 773
消光系数 (M-1cm-1) 199000 量子产量 0.3
CF260 0.022 CF280 0.029

质量控制

化学结构

Cy7 azide (non-sulfonated)

相关生物数据

Cy7 azide (non-sulfonated)