Tyrphostin AG30 (AG30)
mRNA synthesis
In vitro transcription of capped mRNA with modified nucleotides and Poly(A) tail
Tyramide Signal Amplification (TSA)
TSA (Tyramide Signal Amplification), used for signal amplification of ISH, IHC and IC etc.
Phos Binding Reagent Acrylamide
Separation of phosphorylated and non-phosphorylated proteins without phospho-specific antibody
Cell Counting Kit-8 (CCK-8)
A convenient and sensitive way for cell proliferation assay and cytotoxicity assay
SYBR Safe DNA Gel Stain
Safe and sensitive stain for visualization of DNA or RNA in agarose or acrylamide gels.
Inhibitor Cocktails
Protect the integrity of proteins from multiple proteases and phosphatases for different applications.
Tyrphostin AG30(AG30)是一种有效和选择性的EGFR酪氨酸激酶抑制剂。Tyrphostin AG30(AG30)选择性地抑制c-ErbB诱导的自我更新,并能够抑制初级红细胞中c-ErbB对STAT5的激活作用[1-2]。
参考文献:
[1]. Volberg T, Zick Y, Dror R, Sabanay I, Gilon C, Levitzki A, Geiger B. The effect of tyrosine-specific protein phosphorylation on the assembly of adherens-type junctions. EMBO J. 1992 May;11(5):1733-42. PMID: 1316270; PMCID: PMC556631.
[2]. Wessely O, Mellitzer G, von Lindern M, Levitzki A, Gazit A, Ischenko I, Hayman MJ, Beug H. Distinct roles of the receptor tyrosine kinases c-ErbB and c-Kit in regulating the balance between erythroid cell proliferation and differentiation. Cell Growth Differ. 1997 May;8(5):481-93. PMID: 9149900.
Storage | Store at -20°C |
M.Wt | 205.17 |
Cas No. | 122520-79-0 |
Formula | C10H7NO4 |
Synonyms | AG30 |
Solubility | ≥15.5 mg/mL in DMSO |
Chemical Name | (E)-2-cyano-3-(3,4-dihydroxyphenyl)acrylic acid |
SDF | Download SDF |
Canonical SMILES | O=C(O)/C(C#N)=C/C1=CC=C(O)C(O)=C1 |
运输条件 | 蓝冰运输或根据您的需求运输。 |
一般建议 | 不同厂家不同批次产品溶解度各有差异,仅做参考。若实验所需浓度过大至产品溶解极限,请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存,请尽快用完。 |
质量控制和MSDS
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