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NHS-12-Biotin

 
Catalog No.
A8784
生物素化试剂,长链。
组合的产品项目
规格价格库存 数量
100mg
¥ 1,363.00
现货
1g
¥ 7,272.00
现货

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A

Description

NHS-12-Biotin is a derivative of D-biotin, a amine-reactive biotinylation agent, that contains a spacer arm off the valeric acid side chain of D-biotin with an NHS ester group at its end. The NHS ester group at the end of NHS-12-Biotin covalently binds to amine groups in proteins and other molecules forming a stable amide linkage and releasing the NHS group. NHS-12-Biotin has a greater length between a covalently modified molecule and the bicyclic biotin rings than NHS-LC-Biotin, which provides the avidin or streptavidin probes a greater opportunity to reach the binding sites deeply buried inside the surface plane of proteins. NHS-12-Biotin is insoluble in aqueous environments requiring the dissolution of organic solvents prior to the addition to a buffered reaction.

化学属性

StorageStore at -20°C
M.Wt539.64
FormulaC24H37N5O7S
Solubility≥20.65 mg/mL in EtOH; ≥23.15 mg/mL in H2O; ≥44.5 mg/mL in DMSO
Chemical Name2,5-dioxopyrrolidin-1-yl 4-(6-(5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)hexanamido)butanoate
SDFDownload SDF
Canonical SMILESO=C1N[C@@]([H])([C@]([H])(CS2)N1)[C@@H]2CCCCC(NCCCCCC(NCCCC(ON3C(CCC3=O)=O)=O)=O)=O
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