Bcr-Abl
Bcl-Abl is a constitutively activated chimeric tyrosine kinase which is the genetic abnormality expressed in patient with CML (chronic myeloid leukemia).
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A8604 GNF 5Target: Bcr-AblSummary: Bcr-Abl抑制剂 -
A8603 GNF 2Summary: Bcr-Abl抑制剂 -
A8602 AdaphostinSummary: P210 bcr/abl酪氨酸激酶抑制剂 -
A5467 Ponatinib (AP24534)1 Citation中文名: 帕纳替尼Target: VEGFR|PDGFR|Bcr-Abl|FGFR|SrcSummary: pan-BCR-ABL抑制剂，多激酶抑制剂 -
A2133 Saracatinib (AZD0530)3 Citation中文名: 塞卡替尼Target: SrcSummary: Src/Abl抑制剂 -
A1805 Imatinib Mesylate (STI571)中文名: 甲磺酸伊马替尼Target: PDGFR|c-Kit|Bcr-AblSummary: Abl/c-kit/PDGFR抑制剂 -
A2149 Bosutinib (SKI-606)1 Citation中文名: 伯舒替尼Target: Bcr-Abl|SrcSummary: Abl/Src有效的抑制剂 -
A8232 Nilotinib(AMN-107)1 Citation中文名: 尼洛替尼Target: Bcr-AblSummary: 选择性Bcr-Abl 激酶抑制剂 -
A3660 Nilotinib monohydrochloride monohydrate中文名: 尼洛替尼盐酸盐一水合物Summary: Bcr-Abl抑制剂 -
A3017 Dasatinib (BMS-354825)4 Citation中文名: 达沙替尼Summary: Src和BCR-Abl抑制剂