Dehydrogenase - Cell Experiments
Dehydrogenases, belonging to the class of oxidoreductases which catalyze donor-acceptor reactions to transfer electron molecules from the oxidant to the reluctant, are a diverse group of enzymes that are able to transfer one or more hydrides (H-) from a substrate to an electron acceptor, such as nicotinamide adenine dinucleotide (NAD+), nicotinamide adenine dinucleotide phosphate (NADP+) or Riboflavin, through oxidation and reduction. Three commonly studied dehydrogenase enzymes include alcohol dehydrogenase (ADH) which catalyzes the reduction of acetylaldehyde to ethanol in plant cells, succinate dehydrogenase which oxidizes succinate to fumarate, and lactate dehydrogenase which catalyzes the reversible oxidation of lactate to pyruvate.
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- B4929 GSK 2837808ATarget: Lactate Dehydrogenases (LDH)Summary: 乳酸脱氢酶A(LDHA)抑制剂
- A8704 Stiripentol中文名: 司替戊醇Target: Lactate Dehydrogenases (LDH)Summary: LDH抑制剂
- B5508 Alda 1Target: Aldehyde DehydrogenasesSummary: ALDH2激活剂
- B5354 CGP 3466B maleate中文名: 奥米加匹马来酸盐Target: GAPDHSummary: GAPDH抑制剂
- A4351 PluriSIn #1 (NSC 14613)Target: Stearoyl-CoA 9-desaturase (SCD-1)Summary: SCD1抑制剂
- A4333 CPI-6131 CitationTarget: Pyruvate dehydrogenases (PDH)Summary: PDH/α-KGDH抑制剂