Dehydrogenase
Dehydrogenases, belonging to the class of oxidoreductases which catalyze donor-acceptor reactions to transfer electron molecules from the oxidant to the reluctant, are a diverse group of enzymes that are able to transfer one or more hydrides (H-) from a substrate to an electron acceptor, such as nicotinamide adenine dinucleotide (NAD+), nicotinamide adenine dinucleotide phosphate (NADP+) or Riboflavin, through oxidation and reduction. Three commonly studied dehydrogenase enzymes include alcohol dehydrogenase (ADH) which catalyzes the reduction of acetylaldehyde to ethanol in plant cells, succinate dehydrogenase which oxidizes succinate to fumarate, and lactate dehydrogenase which catalyzes the reversible oxidation of lactate to pyruvate.
- B7804 AG-221 (Enasidenib)中文名: 恩西地平Summary: 突变体异柠檬酸脱氢酶2(IDH2)抑制剂
- B6124 Fomepizole中文名: 甲吡唑Summary: 乙醇脱氢酶的竞争性抑制剂
- A1606 L-a-Hydroxyglutaric acid disodium salt中文名: L-2-羟基戊二酸Summary: L-α-羟基戊二酸的盐形式
- A3837 DL-α-Hydroxyglutaric acid disodium saltSummary: α羟基酸
- B6104 BVT 2733Summary: 11β-羟基类固醇脱氢酶1型(11β-HSD1)抑制剂
- A8721 CBR-58841 CitationTarget: 3-phosphoglycerate dehydrogenaseSummary: PHGDH抑制剂
- B4929 GSK 2837808ATarget: Lactate Dehydrogenases (LDH)Summary: 乳酸脱氢酶A(LDHA)抑制剂
- B4928 CVT 10216Summary: 醛脱氢酶2(ALDH2)可逆抑制剂
- A8703 IsosafroleTarget: Lactate Dehydrogenases (LDH)Summary: stiripentol类似物,有效的LDH抑制剂。
- A8704 Stiripentol中文名: 司替戊醇Target: Lactate Dehydrogenases (LDH)Summary: LDH抑制剂