Membrane Transporter/Ion Channel - Selective
Ion channels are pore-forming membrane proteins which allow the flow of ions across the membrane. The ion channels can be broadly grouped into six families including calcium channels, chloride channels, potassium channels, sodium channels, gap junction proteins and porins. Not all ion channels are gated, such as certain type of K+ and Cl– channels, transient receptor potential superfamily of cation channels, the ryanodine receptors and the IP3 receptors, but most Na+, K+, Ca2+ and some Cl– channels are all gated by voltage. Ligand-gated channels are regulated in response to ligand binding (e.g. neurotransmitters signaling). These ligand-gated neurotransmitter receptors are known as ionotropic receptors. Various neurotransmitters couple to ionotropic receptors such as glutamate, acetylcholine, glycine, GABA, and serotonin.
- B4798 Procainamide HCl中文名: 盐酸普鲁卡因胺Target: DNA MethyltransferasesSummary: 钠通道阻滞剂
- B6787 STO-609 acetateTarget: CaM-KKSummary: Ca2+-钙调蛋白依赖性蛋白激酶激酶抑制剂
- B5086 CGP 55845 hydrochlorideTarget: GABAB ReceptorsSummary: GABAB受体拮抗剂
- B7659 Psora 41 CitationTarget: Voltage-gated Potassium (KV) ChannelsSummary: Kv1.3阻断剂
- B7389 EIPA3 CitationTarget: Na /H Exchangers (NHEs)Summary: TRPP3通道抑制剂
- B7388 Valinomycin中文名: 缬氨霉素Target: IonophoresSummary: 钾离子特异性转运体
- B7113 PSB 06126Target: NTPDasesSummary: NTPDase 3抑制剂
- B6214 (RS)-CPPTarget: NMDA ReceptorsSummary: NMDA拮抗剂
- B5515 ProTx IITarget: Voltage-gated Sodium (NaV) ChannelsSummary: NaV1.7通道阻断剂
- B5351 SNX 482Target: Voltage-gated Calcium Channels (CaV)Summary: 电压依赖性R型CaV2.3钙通道阻滞剂