Membrane Transporter/Ion Channel
Ion channels are pore-forming membrane proteins which allow the flow of ions across the membrane. The ion channels can be broadly grouped into six families including calcium channels, chloride channels, potassium channels, sodium channels, gap junction proteins and porins. Not all ion channels are gated, such as certain type of K+ and Cl– channels, transient receptor potential superfamily of cation channels, the ryanodine receptors and the IP3 receptors, but most Na+, K+, Ca2+ and some Cl– channels are all gated by voltage. Ligand-gated channels are regulated in response to ligand binding (e.g. neurotransmitters signaling). These ligand-gated neurotransmitter receptors are known as ionotropic receptors. Various neurotransmitters couple to ionotropic receptors such as glutamate, acetylcholine, glycine, GABA, and serotonin.
- C4593 WZB117Summary: 葡萄糖转运蛋白1(Glut1)抑制剂
- C4563 CapsiconiateSummary: TRPV1激动剂
- C4546 Verruculogen中文名: 疣孢青霉原Summary: Maxi-K钾通道抑制剂
- C4375 Bafilomycin DSummary: 液泡H+ ATP酶(V-ATP酶)抑制剂
- C4398 CP-465022 (maleate)Summary: AMPA拮抗剂
- C4171 Docosahexaenoyl SerotoninSummary: TRPV1通道抑制剂
- C4170 Stearoyl SerotoninSummary: TRPV1通道抑制剂
- C4169 Palmitoyl SerotoninSummary: TRPV1通道抑制剂
- C4167 Oleoyl SerotoninSummary: TRPV1通道抑制剂
- C4082 Eicosapentaenoyl SerotoninSummary: TRPV1通道抑制剂