HDAC
Histone deacetylases (HDACs), known for their ability to target histones as well as more than 50 non-histone proteins, are classified into three major classes according to their homology to yeast proteins, including class I (HDAC1, HDAC2, HDAC3 and HDAC8), class II (HDAC4, HDAC5, HDAC7 and HDAC9) and class IV (HDAC11). HDAC inhibitors, a large group of compounds that is able to induce the accumulation of acetylated histones as well as non-histone proteins, are divided into several structural classes including hydroxamates, cyclic peptides, aliphatic acids and benzamides. HDAC inhibitors have been investigated for their efficacy as anticancer agents in the treatment of a wild range of cancers.
- A3755 Resminostat hydrochlorideSummary: HDAC抑制剂
- A3348 Daminozide中文名: 丁酰肼Target: KDM|PHFSummary: KDM2A抑制剂
- A3305 CHAPSSummary: 用于膜蛋白的两性离子洗涤剂,非变性
- A4105 M3441 CitationTarget: Histone Deacetylases (HDACs)Summary: HDAC抑制剂
- A4104 AR-42 (OSU-HDAC42)2 CitationTarget: Histone Deacetylases (HDACs)Summary: HDAC抑制剂
- A4103 LAQ824 (NVP-LAQ824,Dacinostat)1 Citation中文名: 达诺司他Summary: HDAC抑制剂
- A4102 CI994 (Tacedinaline)1 Citation中文名: 乙酰地那林,他地那兰Target: Histone Deacetylases (HDACs)Summary: HDAC抑制剂
- A4101 Tubastatin A6 CitationTarget: Histone Deacetylases (HDACs)Summary: HDAC6抑制剂
- A4100 Droxinostat2 CitationSummary: HDAC抑制剂
- A4099 Valproic acid sodium salt (Sodium valproate)中文名: 丙戊酸钠Target: Histone Deacetylases (HDACs)Summary: HDAC抑制剂