Apoptosis Inducers
Apoptosis, a programmed cell death to eliminate damaged or abnormal cells, is a highly organized physiological process characterized by condensation of nuclear heterochromatin, cell shrinkage and loss of positional organization of organelles in the cytoplasm. Apoptosis inducers are a collection of compounds that are capable of inducing apoptosis in cells. Apoptosis has been extensively studied in numerous researches, where induction of apoptosis has been associated with a variety of events, including activation of p53 gene, transcription factor NF-κB or caspases. Apoptosis inducers have the potential to be incorporated into the management and therapy or prevention of cancer for their ability to induce apoptosis in cancer cells.
- A3278 Nonivamide (Capsaicin Analog)1 Citation中文名: 香草壬酰胺Target: TRP ChannelSummary: TRPV1受体激动剂
- A3265 Brassinolide中文名: 油菜素内酯Summary: 植物生长调节剂
- A3237 Betulinic acid中文名: 白桦脂酸,桦木酸Target: Aminopeptidases|Topoisomerases|HIVSummary: 抗HIV和抗肿瘤化合物,五环三萜类化合物
- A3218 BAM7Summary: BAX激活剂
- A3118 3,3'-Diindolylmethane中文名: 3,3'-二吲哚甲烷Summary: 抗癌和抗肿瘤剂
- A4234 TW-371 CitationTarget: Bcl-2|Bcl-xl|Mcl-1Summary: Bcl-2抑制剂,抑制Bcl-2、Bcl-XL和Mcl-1。
- A4188 2-Methoxyestradiol (2-MeOE2)2 Citation中文名: 2-甲氧雌二醇Summary: 凋亡、抗增殖和抗血管新生的试剂
- N1719 Kaempferol中文名: 山奈酚,山柰酚Summary: 凋亡诱导剂;抗氧化剂;类黄酮
- A8188 Atractyloside Dipotassium Salt1 Citation中文名: 苍术苷钾盐Target: AATSummary: AAT抑制剂
- A8176 Apicidin2 CitationTarget: Histone Deacetylases (HDACs)Summary: 有效的HDAC抑制剂