Recombinant Human ACE2 Protein (Fc tag), HPLC-verified
mRNA synthesis
In vitro transcription of capped mRNA with modified nucleotides and Poly(A) tail
Tyramide Signal Amplification (TSA)
TSA (Tyramide Signal Amplification), used for signal amplification of ISH, IHC and IC etc.
Phos Binding Reagent Acrylamide
Separation of phosphorylated and non-phosphorylated proteins without phospho-specific antibody
Cell Counting Kit-8 (CCK-8)
A convenient and sensitive way for cell proliferation assay and cytotoxicity assay
SYBR Safe DNA Gel Stain
Safe and sensitive stain for visualization of DNA or RNA in agarose or acrylamide gels.
Inhibitor Cocktails
Protect the integrity of proteins from multiple proteases and phosphatases for different applications.
血管紧张素转换酶2 (ACE2)是羧肽酶ACE的同源物，而羧肽酶可生成血管紧张素II，是肾素-血管紧张素系统(RAS)的主要活性肽。ACE2由805个氨基酸组成的金属蛋白酶的M2家族成员之一，是具有单一胞外催化结构域的I型跨膜糖蛋白，其活性位点域暴露于细胞外表面，可通过利用锌催化反应，锌与活性位点内保守的组氨酸配位，促进水分子对底物羰基键的亲核攻击，形成非共价结合的中间体促进循环肽的代谢。基于核酸序列比对的分子进化分析显示新型冠状病毒与SARS-CoV拥有相同的血管紧张素酶2（ACE2）受体。
本产品为经过优化过的具有更高稳定性的ACE2人源可溶性重组蛋白。
|
Name |
ACE2 Protein, Human, Recombinant (Fc Tag), HPLC-verified |
|
Purity |
>95% by SDS-PAGE and HPLC analyses |
|
Endotoxin level |
< 1.000 Eu/µg |
|
Expression system |
HEK293 Cells |
|
MW |
220 kDa |
|
Nature |
Recombinant |
|
Tags |
His tag C-Terminus |
|
Species |
Human |
|
Form |
Liquid |
|
Constituents |
Supplied as a 0.22 μm filtered solution of PBS, pH 7.4. |
|
Concentration |
1mg/mL |
| Components | PH1013-20 µg | PH1013-100 µg | PH1013-500 µg | PH1013-1 mg |
| Recombinant Human ACE2 Protein (Fc tag), HPLC-verified | 20 µL | 100 µL | 500 µL | 1 mL |
Store the components dry at -80 °C for 18 months. | ||||