MQAE
mRNA synthesis
In vitro transcription of capped mRNA with modified nucleotides and Poly(A) tail
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Phos Binding Reagent Acrylamide
Separation of phosphorylated and non-phosphorylated proteins without phospho-specific antibody
Cell Counting Kit-8 (CCK-8)
A convenient and sensitive way for cell proliferation assay and cytotoxicity assay
SYBR Safe DNA Gel Stain
Safe and sensitive stain for visualization of DNA or RNA in agarose or acrylamide gels.
Inhibitor Cocktails
Protect the integrity of proteins from multiple proteases and phosphatases for different applications.
1-(Ethoxycarbonylmethyl)-6-methoxyquinolinium (bromide),简称MQAE,是一种使用非常广泛的氯离子(Cl-)荧光探针。MQAE是“非比率”氯离子猝灭的荧光指示剂,可用于测量细胞内和细胞外氯化物浓度(最大吸收/发射:350/460 nm)。当氯离子浓度升高时,MQAE的荧光强度随着氯离子浓度的增加而成比例地减少。可以监测浓度小于50 mM的氯离子浓度,而不受pH变化的影响[1]。MQAE具有高水溶性和膜渗透性。与SPQ(6-methoxy-N-(-sulphopropyl)quinolinium)相比,MQAE对Cl-的敏感性更高,荧光量子产率更高。
References:
[1] Verkman AS, Sellers MC, Chao AC, et al. Synthesis and characterization of improved chloride-sensitive fluorescent indicators for biological applications. Anal Biochem. 1989;178(2):355–361.
Physical Appearance | A crystalline solid |
Storage | Store at -20°C |
M.Wt | 326.19 |
Cas No. | 162558-52-3 |
Formula | C14H16BrNO3 |
Solubility | ≥45 mg/mL in DMSO; ≥48 mg/mL in EtOH; ≥48.3 mg/mL in H2O |
Chemical Name | 1-(2-ethoxy-2-oxoethyl)-6-methoxyquinolin-1-ium bromide |
SDF | Download SDF |
Canonical SMILES | O=C(C[N+]1=CC=CC2=CC(OC)=CC=C21)OCC.[Br-] |
运输条件 | 蓝冰运输或根据您的需求运输。 |
一般建议 | 不同厂家不同批次产品溶解度各有差异,仅做参考。若实验所需浓度过大至产品溶解极限,请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存,请尽快用完。 |
质量控制和MSDS
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