Ziprasidone hydrochloride monohydrate
盐酸齐拉西酮水合物
Catalog No.
A3953
5-HT（5-羟色胺）/多巴胺受体拮抗剂
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Ziprasidone is a combined 5-HT (serotonin) and dopamine receptor antagonist which exhibits potent effects in preclinical assays predictive of antipsychotic activity. Whereas Ziprasidone is a dopamine antagonist in vitro and in vivo, its most potent action is antagonism of 5-HT2A receptors, where its affinity is an order of magnitude greater than that observed for dopamine D2 sites. Additionally, Ziprasidone inhibits neuronal uptake of 5-HT and norepinephrine comparable to the antidepressant imipramine. Ziprasidone differs from other atypical antipsychotic drugs in several clinically important ways, although further experience is necessary to clarify the significance of these differences.
| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 467.41 |
| Cas No. | 138982-67-9 |
| Formula | C21H24Cl2N4O2S |
| Synonyms | CP 88059;CP-88059;CP88059 |
| Solubility | insoluble in H2O; insoluble in EtOH; ≥11.69 mg/mL in DMSO |
| Chemical Name | 5-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]-6-chloro-1,3-dihydroindol-2-one;hydrate;hydrochloride |
| SDF | Download SDF |
| Canonical SMILES | C1CN(CCN1CCC2=C(C=C3C(=C2)CC(=O)N3)Cl)C4=NSC5=CC=CC=C54.O.Cl |
| 运输条件 | 蓝冰运输或根据您的需求运输。 |
| 一般建议 | 不同厂家不同批次产品溶解度各有差异，仅做参考。若实验所需浓度过大至产品溶解极限，请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存，请尽快用完。 |
质量控制和MSDS
- 批次:
化学结构
