U-104
mRNA synthesis
In vitro transcription of capped mRNA with modified nucleotides and Poly(A) tail
Tyramide Signal Amplification (TSA)
TSA (Tyramide Signal Amplification), used for signal amplification of ISH, IHC and IC etc.
Phos Binding Reagent Acrylamide
Separation of phosphorylated and non-phosphorylated proteins without phospho-specific antibody
Cell Counting Kit-8 (CCK-8)
A convenient and sensitive way for cell proliferation assay and cytotoxicity assay
SYBR Safe DNA Gel Stain
Safe and sensitive stain for visualization of DNA or RNA in agarose or acrylamide gels.
Inhibitor Cocktails
Protect the integrity of proteins from multiple proteases and phosphatases for different applications.
U-104是碳酸酐酶IX（CAIX）的新型脲基磺酰胺抑制剂。肿瘤体积测量显示，相对于载体对照组，U-104化合物可以抑制小鼠原发肿瘤生长。在4T1实验性癌转移模型中，它还具有抑制癌转移形成的能力。
参考文献：
Yuanmei Lou, Paul C. McDonald, Arusha Oloumi, Stephen Chia, Christina Ostlund, Ardalan Ahmadi, Alastair Kyle, Ulrich auf dem Keller, Samuel Leung, David Huntsman, Blaise Clarke, Brent W. Sutherland, Dawn Waterhouse, Marcel Bally, Calvin Roskelley, Christopher M. Overall, Andrew Minchinton, Fabio Pacchiano, Fabrizio Carta, Andrea Scozzafava, Nadia Touisni, Jean-Yves Winum, Claudiu T. Supuran, Shoukat Dedhar. Targeting Tumor Hypoxia: Suppression of Breast Tumor Growth and Metastasis by Novel Carbonic Anhydrase IX Inhibitors. Cancer Research May 1, 2011 71; 3364
| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 309.32 |
| Cas No. | 178606-66-1 |
| Formula | C13H12FN3O3S |
| Solubility | insoluble in H2O; ≥11.5 mg/mL in DMSO; ≥9.14 mg/mL in EtOH with gentle warming and ultrasonic |
| Chemical Name | 1-(4-fluorophenyl)-3-(4-sulfamoylphenyl)urea |
| SDF | Download SDF |
| Canonical SMILES | C1=CC(=CC=C1NC(=O)NC2=CC=C(C=C2)S(=O)(=O)N)F |
| 运输条件 | 蓝冰运输或根据您的需求运输。 |
| 一般建议 | 不同厂家不同批次产品溶解度各有差异，仅做参考。若实验所需浓度过大至产品溶解极限，请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存，请尽快用完。 |
质量控制和MSDS
- 批次:
化学结构
