Tamoxifen Citrate
mRNA synthesis
In vitro transcription of capped mRNA with modified nucleotides and Poly(A) tail
Tyramide Signal Amplification (TSA)
TSA (Tyramide Signal Amplification), used for signal amplification of ISH, IHC and IC etc.
Phos Binding Reagent Acrylamide
Separation of phosphorylated and non-phosphorylated proteins without phospho-specific antibody
Cell Counting Kit-8 (CCK-8)
A convenient and sensitive way for cell proliferation assay and cytotoxicity assay
SYBR Safe DNA Gel Stain
Safe and sensitive stain for visualization of DNA or RNA in agarose or acrylamide gels.
Inhibitor Cocktails
Protect the integrity of proteins from multiple proteases and phosphatases for different applications.
Tamoxifen Citrate是一种抗雌激素药[1].
Tamoxifen Citrate作为一种抗雌激素药,可以抑制雌激素结合雌激素受体.Tamoxifen在乳腺组织中拮抗雌激素作用,因而抑制肿瘤生长.据发现,Tamoxifen能抑制雌激素调节基因的表达,包括肿瘤分泌的生长因子和血管生成因子.Tamoxifen也可以使细胞周期阻滞于G1期并减缓细胞增殖.此外,Tamoxifen能直接诱导程序性细胞死亡[1].
参考文献：
[1] Osborne CK. Tamoxifen in the treatment of breast cancer. N Engl J Med. 1998 Nov 26;339(22):1609-18.
| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 563.64 |
| Cas No. | 54965-24-1 |
| Formula | C32H37NO8 |
| Solubility | ≥28.2 mg/mL in Etoh with gentle warming; insoluble in H2O; ≥97 mg/mL in DMSO |
| Chemical Name | 2-[4-[(Z)-1,2-diphenylbut-1-enyl]phenoxy]-N,N-dimethylethanamine;2-hydroxypropane-1,2,3-tricarboxylic acid |
| SDF | Download SDF |
| Canonical SMILES | CCC(=C(C1=CC=CC=C1)C2=CC=C(C=C2)OCCN(C)C)C3=CC=CC=C3.C(C(=O)O)C(CC(=O)O)(C(=O)O)O |
| 运输条件 | 蓝冰运输或根据您的需求运输。 |
| 一般建议 | 不同厂家不同批次产品溶解度各有差异，仅做参考。若实验所需浓度过大至产品溶解极限，请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存，请尽快用完。 |
质量控制和MSDS
- 批次:
化学结构
