Transferase
Transferases are a collection of a large and diverse group of enzymes that specifically catalyze the transfer of one or more functional groups from one molecule (the donor) to another (the acceptor). A few transferases involved in this category include farnesyltransferase (FTase), diacylglycerol acyltransferase (DGAT) and catechol-O-methyltransferase (COMT). Ftase catalyzes the transfer of a farnesyl moiety to the cysteine terminal residue (the sulfhydryl cysteine of the CAAS motif)) of substrate proteins. DGAT catalyzes the final step of the triacylglycerol (TG) biosynthetic pathway, where diacylglycerol is esterified to produce TG. COMT catalyzes the methylation of catechol substrates utilizing S-adenosyl-L-methionine (SAM) as a methyl donor and generating O-methylated catechol and S-adenosyl-L-homocysteine.
- C4135 OU749Summary: γ-谷氨酰转移酶(GGT)抑制剂
- C3463 BCATc Inhibitor 2Summary: 胞浆BCAT(BCATc)抑制剂
- C3203 FTase Inhibitor IISummary: Ftase抑制剂
- B6134 Amodiaquine dihydrochloride dihydrate中文名: 盐酸阿莫地喹二水合物Summary: 组胺N-甲基转移酶抑制剂
- B6062 Manumycin A中文名: 手霉素ASummary: 法尼基转移酶抑制剂
- B5842 FTI 277 HClSummary: FTase抑制剂
- B5729 GPP 78 hydrochlorideSummary: NAMPT抑制剂
- B5521 LY 78335Summary: 苯乙醇胺-N-甲基转移酶(PNMT)抑制剂
- B7402 Tris DBASummary: N-肉豆蔻酰转移酶-1(NMT-1)抑制剂
- B6331 SKF 91488 dihydrochlorideSummary: 组胺N-甲基转移酶抑制剂