P450
Cytochrome P450 are a family of heme-containing monoxygenases catalyzing the metabolism of xenobiotics in the body where P450 enzymes use O2 and two electrons provided by NAD(P)H with the help of redox partner flavoproteins and iron-sulfur proteins to catalyze the monooxygenation of a variety of substrates. Based on how electrons from NAD(P)H are delivered to the catalytic site, P450 enzymes are divided into four classes, including Class I requiring both an FAD-containing reductase and an iron sulfur redoxin, Class II requiring only an FAD/FMN-containg P450 reductase, Class III requiring no electron donor and Class IV requiring electrons directly from NAD(P)H.
- C7063 2,6-Dihydroxyanthraquinone
- C5554 Thienyldecyl IsothiocyanateSummary: 细胞色素P450抑制剂
- C5344 HET0016Summary: 20-HETE形成的抑制剂
- C5076 Uniconazole中文名: 烯效唑Summary: 细胞色素P450 707As抑制剂
- C5047 2-Phenyl-2-(1-piperidinyl)propaneSummary: 基于机制的人细胞色素P450(CYP)2B6失活剂
- C4647 β-NicotyrineSummary: 细胞色素P450(CYP)亚型CYP2A6和CYP2A13抑制剂
- C4562 2,3-dihydrothieno-Thiadiazole CarboxylateSummary: CYP450酶(CYP2E1和CYP2B4)抑制剂
- C4429 4-phenyl-5-methyl-1,2,3-ThiadiazoleSummary: CYP2B4和CYP2E1抑制剂
- C4253 RhapontigeninSummary: 细胞色素P450 1A1的失活剂,具有抗氧化和抗癌活性
- C4131 Sulfaphenazole中文名: 磺胺苯吡唑Summary: CYP2C9抑制剂