Dehydrogenase
Dehydrogenases, belonging to the class of oxidoreductases which catalyze donor-acceptor reactions to transfer electron molecules from the oxidant to the reluctant, are a diverse group of enzymes that are able to transfer one or more hydrides (H-) from a substrate to an electron acceptor, such as nicotinamide adenine dinucleotide (NAD+), nicotinamide adenine dinucleotide phosphate (NADP+) or Riboflavin, through oxidation and reduction. Three commonly studied dehydrogenase enzymes include alcohol dehydrogenase (ADH) which catalyzes the reduction of acetylaldehyde to ethanol in plant cells, succinate dehydrogenase which oxidizes succinate to fumarate, and lactate dehydrogenase which catalyzes the reversible oxidation of lactate to pyruvate.
- B5799 Qc 1Summary: 苏氨酸脱氢酶(TDH)抑制剂
- B5643 TC HSD 21Summary: 17β-羟基类固醇脱氢酶3(17β-HSD3)抑制剂
- B5508 Alda 1Target: Aldehyde DehydrogenasesSummary: ALDH2激活剂
- B5354 CGP 3466B maleate中文名: 奥米加匹马来酸盐Target: GAPDHSummary: GAPDH抑制剂
- B5716 GalloflavinSummary: 人乳酸脱氢酶(LDH)抑制剂
- B5697 WIN 18446Summary: 醛脱氢酶1a2(ALDH1a2)抑制剂
- B7725 MethylmalonateSummary: 可逆的琥珀酸脱氢酶抑制剂
- B4669 VidofludimusSummary: DHODH 抑制剂
- A3146 AGI-6780Target: IDH2Summary: IDH2/R140Q突变抑制剂
- A4351 PluriSIn #1 (NSC 14613)Target: Stearoyl-CoA 9-desaturase (SCD-1)Summary: SCD1抑制剂