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EP4 Receptor

EP4 receptor is a G-protein coupled receptor for prostaglandin E2. It bind to Gαs and activate adenylyl cyclase to stimulate the formation of cAMP and induce smooth muscle relaxation. It may involve in the renal/intestinal/adrenal/uterine function.

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 Paper Citing APExBIO Products  Ongoing Clinical Trials  Solubility in DMSO  Solubility in Water  Solubility in Ethanol  Solubility in Dimethyl Formamide
  1. ONO-AE3-208
    A3684 ONO-AE3-208
     2 Citation
    Summary: 高亲和力的EP4受体选择性拮抗剂
      ≥40.4 mg/mL
      ≥8.1 mg/mL
      <2.68 mg/mL
  2. MK-2894
    A3613 MK-2894
    Summary: EP4受体抑制剂
      soluble in dmso

2 件产品

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