Endocrinology and Hormones - Cancer
There are three types of hormones based on their chemical composition: Amines (e.g. dopamine, adrenalin and noradrenalin); Steroids (e.g. estrogen, testosterone and glucocorticoids); Peptides (e.g. the peptide hormones insulin, ghrelin and vasopressin). Peptide hormones produced by secretory nervous tissue are known as neuropeptides. For example, thyroid hormone plays important parts in development, homeostasis and metabolism, while cortisol is essential for growth, nutrient supply and immune function. Moreover, the regulation of blood glucose involves several pancreatic peptide insulin and its counter regulatory hormone, glucagon, as well as cortisol, growth hormone and epinephrine.
Dysregulations in endocrine system are implicated in diseases such as Acromegaly, Cushing Syndrome, Diabetes, Dwarfism, Graves Disease, Hermaphroditism, Delayed and Precocious Puberty and Thyroid Diseases.
- A5065 Bicalutamide1 Citation中文名: 比卡鲁胺Target: Androgen ReceptorsSummary: 雄激素受体(Androgen receptor)拮抗剂
- A8452 ODM-201中文名: 达洛鲁胺Target: Androgen ReceptorsSummary: 新一代雄激素受体抑制剂
- B5469 G-153 CitationTarget: GPR30Summary: GPER受体拮抗剂
- B5455 G-14 CitationTarget: GPR30Summary: GPR30激动剂
- B5421 (Z)-4-Hydroxytamoxifen中文名: 4-羟基他莫昔芬Target: Estrogen and Related ReceptorsSummary: 雌激素受体(ER)调节剂
- B6429 Naltrindole hydrochloride中文名: 纳曲吲哚盐酸盐Summary: δ阿片样物质拮抗剂
- B1510 Medroxyprogesterone acetate中文名: 醋酸甲羟孕酮Target: Progesterone ReceptorsSummary: 类固醇孕激素
- B1518 Erteberel (LY500307)Target: Estrogen and Related ReceptorsSummary: ERβ激动剂
- B1394 Tamoxifen Citrate中文名: 枸橼酸他莫昔Target: Estrogen and Related ReceptorsSummary: 抗雌激素药
- B1515 Raloxifene HCl中文名: 盐酸雷洛昔芬Target: Estrogen and Related ReceptorsSummary: 雌激素受体(ER)调节剂