Endocrinology and Hormones
There are three types of hormones based on their chemical composition: Amines (e.g. dopamine, adrenalin and noradrenalin); Steroids (e.g. estrogen, testosterone and glucocorticoids); Peptides (e.g. the peptide hormones insulin, ghrelin and vasopressin). Peptide hormones produced by secretory nervous tissue are known as neuropeptides. For example, thyroid hormone plays important parts in development, homeostasis and metabolism, while cortisol is essential for growth, nutrient supply and immune function. Moreover, the regulation of blood glucose involves several pancreatic peptide insulin and its counter regulatory hormone, glucagon, as well as cortisol, growth hormone and epinephrine.
Dysregulations in endocrine system are implicated in diseases such as Acromegaly, Cushing Syndrome, Diabetes, Dwarfism, Graves Disease, Hermaphroditism, Delayed and Precocious Puberty and Thyroid Diseases.
- C5637 Lasofoxifene (tartrate)中文名: 酒石酸拉索昔芬Summary: 第三代非甾体选择性雌激素受体调节剂(SERM)
- C5014 3,3',5'-Triiodo-L-thyronineSummary: TRΔα1激活剂
- C4792 ML-335Summary: OPRM1-OPRD1异源二聚化的激动剂
- C4747 OrmeloxifeneSummary: 雌激素受体调节剂
- C4624 4’-hydroxy Tamoxifen中文名: 4-羟基他莫昔芬Summary: 雌激素受体调节剂他莫昔芬(tamoxifen)的代谢物
- C4768 GSK2881078Summary: 选择性雄激素受体调节剂(SARM)
- C4481 8-Prenylnaringenin中文名: 8-异戊烯基柚皮素Summary: 雌激素受体抑制剂
- C4721 2-hydroxy FlutamideSummary: 雄激素受体抑制剂
- C4274 Quinestrol中文名: 炔雌醚,炔雌醇环戊醚Summary: 在激素替代疗法中有效的合成雌激素
- C4317 5α-dihydro-11-keto Testosterone中文名: 11-酮二氢睾酮Summary: 雄激素受体激动剂