HDAC
Histone deacetylases (HDACs), known for their ability to target histones as well as more than 50 non-histone proteins, are classified into three major classes according to their homology to yeast proteins, including class I (HDAC1, HDAC2, HDAC3 and HDAC8), class II (HDAC4, HDAC5, HDAC7 and HDAC9) and class IV (HDAC11). HDAC inhibitors, a large group of compounds that is able to induce the accumulation of acetylated histones as well as non-histone proteins, are divided into several structural classes including hydroxamates, cyclic peptides, aliphatic acids and benzamides. HDAC inhibitors have been investigated for their efficacy as anticancer agents in the treatment of a wild range of cancers.
- A4496 NSC 3852Target: Histone Deacetylases (HDACs)Summary: HDAC抑制剂
- A4495 NCH 51Summary: 组蛋白去乙酰化酶(HDAC)抑制剂
- A4493 KD 51701 CitationSummary: HDAC抑制剂
- A3860 Tasquinimod中文名: 他喹莫德Summary: 抗血管生成和抗肿瘤剂
- A3761 RG2833Target: HDACSummary: 脑渗透性HDAC抑制剂
- A3755 Resminostat hydrochlorideSummary: HDAC抑制剂
- A3348 Daminozide中文名: 丁酰肼Target: KDM|PHFSummary: KDM2A抑制剂
- A3305 CHAPSSummary: 用于膜蛋白的两性离子洗涤剂,非变性
- A4105 M3441 CitationTarget: Histone Deacetylases (HDACs)Summary: HDAC抑制剂
- A4104 AR-42 (OSU-HDAC42)2 CitationTarget: Histone Deacetylases (HDACs)Summary: HDAC抑制剂