Apoptosis Inducers
Apoptosis, a programmed cell death to eliminate damaged or abnormal cells, is a highly organized physiological process characterized by condensation of nuclear heterochromatin, cell shrinkage and loss of positional organization of organelles in the cytoplasm. Apoptosis inducers are a collection of compounds that are capable of inducing apoptosis in cells. Apoptosis has been extensively studied in numerous researches, where induction of apoptosis has been associated with a variety of events, including activation of p53 gene, transcription factor NF-κB or caspases. Apoptosis inducers have the potential to be incorporated into the management and therapy or prevention of cancer for their ability to induce apoptosis in cancer cells.
- A4450 CHM 1Summary: 微管蛋白聚合抑制剂
- A4449 C 75Summary: 脂肪酸合酶(FAS)抑制剂
- A4447 2,3-DCPE hydrochlorideTarget: Apoptosis InducersSummary: Bcl-XL蛋白表达下调剂
- A3886 Trabectedin中文名: 曲贝替定Summary: 抗肿瘤剂
- A3826 SMIP004Summary: 细胞凋亡诱导剂
- A3746 R1530Summary: 抗血管生成,有丝分裂-血管生成抑制剂(MAI)
- A3583 Matrine中文名: 苦参碱Summary: 在槐属植物中发现的生物碱
- A3424 Gambogic Acid中文名: 藤黄酸Summary: Caspase激活剂和凋亡诱导剂
- A3335 Curcumin1 Citation中文名: 姜黄素Target: Histone Deacetylases (HDACs)|Nrf2|Histone Acetyltransferases (HATs)|TyrosinasesSummary: Tyrosinase(酪氨酸酶)抑制剂
- A3327 Costunolide中文名: 木香烃内酯Target: FPTase|TelomerasesSummary: BMM分化抑制剂