Apoptosis Inducers
Apoptosis, a programmed cell death to eliminate damaged or abnormal cells, is a highly organized physiological process characterized by condensation of nuclear heterochromatin, cell shrinkage and loss of positional organization of organelles in the cytoplasm. Apoptosis inducers are a collection of compounds that are capable of inducing apoptosis in cells. Apoptosis has been extensively studied in numerous researches, where induction of apoptosis has been associated with a variety of events, including activation of p53 gene, transcription factor NF-κB or caspases. Apoptosis inducers have the potential to be incorporated into the management and therapy or prevention of cancer for their ability to induce apoptosis in cancer cells.
- B4760 Raltegravir potassium salt中文名: 雷特格韦钾盐Summary: HIV整合酶抑制剂
- B7760 CFM 4Summary: 干扰CARP-1与APC-2的结合
- B3255 Meisoindigo中文名: 甲异靛Summary: 细胞凋亡诱导剂;AML 潜在药物
- A1984 Bendamustine HCl中文名: 盐酸苯达莫司汀Summary: 用于非霍奇金淋巴瘤的细胞生长抑制剂
- A4453 NSC 687852 (b-AP15)Target: Deubiquitinating enzymes (DUBs)Summary: 19S调节颗粒抑制剂
- A4457 Streptozocin1 Citation中文名: 链脲佐菌素Summary: 抗生素和抗肿瘤剂
- A4456 Plumbagin中文名: 白花丹素Summary: 抗癌剂
- A4455 Piperlongumine中文名: 荜茇酰胺Summary: 细胞死亡诱导剂
- A4454 Oncrasin 1Summary: 促凋亡剂
- A4451 Deguelin中文名: 魚藤素Summary: 抗癌和抗病毒剂