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Safinamide

沙芬酰胺
Catalog No.
A3784
MAO-B抑制剂
组合的产品项目
规格价格库存 数量
10mg
¥ 727.00
现货
50mg
¥ 2,272.00
现货
500mg
¥ 6,818.00
现货

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A

背景

Safinamide (EMD 1195686; FCE 26743; ) is a highly selective and reversible monoamine oxidase type B (MAO-B) inhibitor that increases neostriatal dopamine concentration. In addition, Safinamide (EMD 1195686; FCE 26743; ) is voltage-dependent sodium and calcium channel blocker. Safinamide (EMD 1195686; FCE 26743; ) appears to bind to the batrachotoxin-sensitive site 2 of the voltage-sensitive sodium channels. Safinamide blocks N and L-type calcium channels and inhibits glutamate and aspartate release from synaptic terminals.

化学属性

StorageStore at -20°C
M.Wt302.34
Cas No.133865-89-1
FormulaC17H19FN2O2
SynonymsEMD 1195686;FCE 26743;EMD-1195686;EMD1195686;FCE-26743
Solubility≥32.3 mg/mL in DMSO; ≥13.95 mg/mL in EtOH; insoluble in H2O
Chemical Name(2S)-2-[[4-[(3-fluorophenyl)methoxy]phenyl]methylamino]propanamide
SDFDownload SDF
Canonical SMILESCC(C(=O)N)NCC1=CC=C(C=C1)OCC2=CC(=CC=C2)F
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