• 欢迎来到美国APExBIO中文站,专注小分子抑制剂、激动剂、拮抗剂及化合物库!

 


加 微 信 得 红 包
ApexBio
Search Site
首页 >> Signaling Pathways >> Apoptosis >> Bcl-2 Family

Bcl-2 Family

Bcl-2 family proteins are a group of proteins homologous to the Bcl-2 protein and characterized by containing at least one of four conserved Bcl-2 homology (BH) domains (BH1, BH2, BH3 and BH4). Bcl-2 family proteins, consisting of pro-apoptotic and anti-apoptotic molecules, can be classified into the following three subfamilies according to sequence homology within four BH domains: (1) a subfamily shares sequence homology within all four BH domains, such as Bcl-2, Bcl-XL and Bcl-w which are anti-apoptotic; (2) a subfamily shares sequence homology within BH1, BH2 and BH4, such as Bax and Bak which are pro-apoptotic; (3) a subfamily shares sequence homology only within BH3, such as Bik and Bid which are pro-apoptotic.

Research Area
Compare Products

生化试剂

  1. 产品编号 产品名称 信息
  2. A3935 WEHI-539 选择性的Bcl-xL抑制剂
  3. B6094 BH3I-1 Bcl-2或Bcl-XL抑制剂
  4. A8737 S63845 MCL1抑制剂
  5. B6011 A-1210477 MCL-1抑制剂
  6. B5978 BDA-366 BCL2 BH4 结构域的选择性拮抗剂
  7. B5846 Radotinib(IY-5511) Bcr-Abl酪氨酸激酶抑制剂
  8. B4902 (+)-Apogossypol Bcl-2家族蛋白抑制剂
  9. B4901 Pyridoclax Mcl-1抑制剂
  10. B4881 UMI-77 Mcl-1抑制剂
  11. A8194 ABT-199 选择性的Bcl-2抑制剂
  12. A8193 ABT-737 Top Seller Bcl-2抑制剂
  13. A3007 ABT-263 (Navitoclax) Bcl-2家族抑制剂,可以抑制Bcl-2、 Bcl-xL和Bcl-w。
  14. A4234 TW-37 Top Seller Bcl-2抑制剂,抑制Bcl-2、Bcl-XL和Mcl-1。
  15. A9902 Bcl Family Set I Bcl家族抑制剂
  16. A4194 Obatoclax mesylate (GX15-070) 强效的BCL-2抑制剂
  17. A8168 HA14-1 Top Seller 有效的、细胞通透的Bcl-2抑制剂
  18. B1080 Marinopyrrole A 选择性Mcl-1抑制剂
  19. A4461 Bax inhibitor peptide V5 Bax抑制剂
  20. A4460 Bax inhibitor peptide P5 Bax抑制剂
  21. A3218 BAM7 BAX激活剂
  22. A4199 Sabutoclax Pan-Bcl-2抑制剂
  23. A4200 Apogossypolone (ApoG2) Bcl-2的非肽类小分子抑制剂
  24. A4198 BM-1074 Bcl-2/Bcl-xL 抑制剂
  25. A4459 Bax channel blocker Bax介导的线粒体细胞色素c释放的抑制剂
  26. A4462 Bax inhibitor peptide, negative control 抑制Bax易位到线粒体的多肽
  27. A4463 BIM, Biotinylated 连接有生物素部分的Bim肽片段
  28. A4464 iMAC2 MAC抑制剂
  29. A4465 MIM1 Mcl-1抑制剂
  30. A4466 Muristerone A TRAIL和hFasL诱导的凋亡抑制剂
  31. N2135 Gossypol PAF抑制剂,抗生育和抗癌
  32. A4447 2,3-DCPE hydrochloride Bcl-XL蛋白表达下调剂
  33. A3196 AT-101 BH3-类似物,棉酚对映异构体
  34. A3424 Gambogic Acid Caspase激活剂和凋亡诱导剂