Pyrazinamide
mRNA synthesis
In vitro transcription of capped mRNA with modified nucleotides and Poly(A) tail
Tyramide Signal Amplification (TSA)
TSA (Tyramide Signal Amplification), used for signal amplification of ISH, IHC and IC etc.
Phos Binding Reagent Acrylamide
Separation of phosphorylated and non-phosphorylated proteins without phospho-specific antibody
Cell Counting Kit-8 (CCK-8)
A convenient and sensitive way for cell proliferation assay and cytotoxicity assay
SYBR Safe DNA Gel Stain
Safe and sensitive stain for visualization of DNA or RNA in agarose or acrylamide gels.
Inhibitor Cocktails
Protect the integrity of proteins from multiple proteases and phosphatases for different applications.
| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 123.11 |
| Cas No. | 98-96-4 |
| Formula | C5H5N3O |
| Solubility | ≥2.94 mg/mL in EtOH with gentle warming and ultrasonic; ≥5.35 mg/mL in DMSO; ≥7.45 mg/mL in H2O with ultrasonic |
| Chemical Name | pyrazine-2-carboxamide |
| SDF | Download SDF |
| Canonical SMILES | C1=CN=C(C=N1)C(=O)N |
| 运输条件 | 蓝冰运输或根据您的需求运输。 |
| 一般建议 | 不同厂家不同批次产品溶解度各有差异，仅做参考。若实验所需浓度过大至产品溶解极限，请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存，请尽快用完。 |
| 细胞实验 [1]： | |
|
细胞系 |
结核分枝杆菌H37Rv |
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溶解方法 |
在DMSO中的溶解度≥5.35mg/mL。为了获得更高的浓度，可以将离心管在37℃加热10分钟和/或在超声波浴中震荡一段时间。原液可以在-20℃以下储存几个月。 |
|
反应条件 |
12 mg/ml |
|
应用 |
粗制分枝杆菌细胞提取物中脂肪酸合成的分析表明，吡嗪酸未能直接调节由脂肪酸合酶I（FAS-1）催化的脂肪酸合酶活性。 但是，5-氯吡嗪酰胺以时间依赖性方式不可逆地抑制脂肪酸的合成。 此外，我们证明吡嗪酸不抑制纯化的分枝杆菌FAS-1，这表明该酶不是吡嗪酰胺的直接靶标。 |
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References: [1]. Boshoff HI, Mizrahi V, Barry CE 3rd. Effects of pyrazinamide on fatty acid synthesis by whole mycobacterial cells and purified fatty acid synthase I. J Bacteriol. 2002 Apr;184(8):2167-72. PubMed PMID: 11914348; PubMed Central PMCID: PMC134955. |
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质量控制和MSDS
- 批次:
化学结构
