Platelet Membrane Glycoprotein IIB Peptide (296-306)
mRNA synthesis
In vitro transcription of capped mRNA with modified nucleotides and Poly(A) tail
Tyramide Signal Amplification (TSA)
TSA (Tyramide Signal Amplification), used for signal amplification of ISH, IHC and IC etc.
Phos Binding Reagent Acrylamide
Separation of phosphorylated and non-phosphorylated proteins without phospho-specific antibody
Cell Counting Kit-8 (CCK-8)
A convenient and sensitive way for cell proliferation assay and cytotoxicity assay
SYBR Safe DNA Gel Stain
Safe and sensitive stain for visualization of DNA or RNA in agarose or acrylamide gels.
Inhibitor Cocktails
Protect the integrity of proteins from multiple proteases and phosphatases for different applications.
对Bak或Bakb等位基因具有特异性的人类同种抗血清仅与膜糖蛋白(GP)IIb的重链发生反应。
GPllb是由一个125 Kd的重链和23 Kd的轻链通过二硫键连接组成的。cDNA序列的亲水性分析表明,GPllb通过位于轻链C末端的20个氨基酸的单一跨膜结构域锚定至血小板。
GPllb-IIa复合体是Ca2+依赖的异源二聚体,存在于活化的血小板中,可以与四种不同的粘合蛋白之一结合,即血纤维蛋白原、纤连蛋白、血管性血友病因子或玻连蛋白。
参考文献:
1. Bray PF, Rosa J-P, Lingappa VR, Kan YW, McEver RP, Shuman MA: Biogenesis of the platelet receptor for fibrinogen: Evidence for separate precursors for glycoproteins Ilb and IIIa. Proc Natl Acad Sci USA 83:1480,1986
2. Silver SM, McDonough MM, Vilaire G, Bennett JS: The in vitro synthesis of polypeptides for the platelet membrane glycoproteins IIb and IIIa. Blood 69:1031, 1987.
3. Phillips DR, Charo IF, Parise LV, Fitzgerald LA : The platelet membrane glycoproteins IIb-IIIa co,plex. Blood 71:831-843, 1988
Physical Appearance | A solid |
Storage | Store at -20°C |
M.Wt | 1198.2 |
Formula | C47H75N17O20 |
Synonyms | H2N-Thr-Asp-Val-Asn-Gly-Asp-Gly-Arg-His-Asp-Leu-OH |
Solubility | ≥119.8 mg/mL in DMSO; ≥5 mg/mL in EtOH with ultrasonic; ≥50 mg/mL in H2O |
SDF | Download SDF |
Canonical SMILES | N[C@@H]([C@H](C)O)C(N[C@@H](CC(O)=O)C(N[C@@H](C(C)C)C(N[C@@H](CC(N)=O)C(NCC(N[C@@H](CC(O)=O)C(NCC(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC1=CNC=N1)C(N[C@@H](CC(O)=O)C(N[C@@H](CC(C)C)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O |
运输条件 | 蓝冰运输或根据您的需求运输。 |
一般建议 | 不同厂家不同批次产品溶解度各有差异,仅做参考。若实验所需浓度过大至产品溶解极限,请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存,请尽快用完。 |
质量控制和MSDS
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