Neostigmine Bromide
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Cell Counting Kit-8 (CCK-8)
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SYBR Safe DNA Gel Stain
Safe and sensitive stain for visualization of DNA or RNA in agarose or acrylamide gels.
Inhibitor Cocktails
Protect the integrity of proteins from multiple proteases and phosphatases for different applications.
Neostigmine Bromide是乙酰胆碱酯酶（acetylcholinesterase）的可逆抑制剂[1]。
乙酰胆碱酯酶（AChE）是一种水解酶，可以水解神经肌肉接头和胆碱能突触的神经递质乙酰胆碱，它终止信号转导，引发神经元细胞凋亡。
Neostigmine bromide是一种季胺类物质，可以阻断胆碱酯酶的活性，扩展和增强乙酰胆碱的毒蕈碱和烟碱效应。参与治疗原发性开角型青光眼、术后尿潴留、麻痹性肠梗阻和重症肌无力等。有报道称，Neostigmine bromide可以作为治疗妇科或腹部手术后疼痛的局部麻醉药和阿片类药物的辅助药物[1]。
参考文献：
[1] El-Kosasy AM, Nebsen M, Abd El-Rahman MK, Salem MY, El-Bardicy MG. Comparative study of 2-hydroxy propyl beta cyclodextrin and calixarene as ionophores in potentiometric ion-selective electrodes for neostigmine bromide. Talanta. 2011 Aug 15;85(2):913-8.
| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 303.2 |
| Cas No. | 114-80-7 |
| Formula | C12H19N2O2·Br |
| Solubility | ≥15.16 mg/mL in H2O; ≥29.2 mg/mL in EtOH; ≥45.3 mg/mL in DMSO |
| Chemical Name | [3-(dimethylcarbamoyloxy)phenyl]-trimethylazanium;bromide |
| SDF | Download SDF |
| Canonical SMILES | CN(C)C(=O)OC1=CC=CC(=C1)[N+](C)(C)C.[Br-] |
| 运输条件 | 蓝冰运输或根据您的需求运输。 |
| 一般建议 | 不同厂家不同批次产品溶解度各有差异，仅做参考。若实验所需浓度过大至产品溶解极限，请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存，请尽快用完。 |
质量控制和MSDS
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化学结构
