INCB 3284 dimesylate
Catalog No.
A3492
HCCR2 antagonist
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INCB 3284 is a potent, selective and orally bioavailable hCCR2 antagonist. INCB 3284 exhibits potenct antagonism against monocyte chemoattractant molecule binding to hCCR2 and chemotaxis activity (IC50 values are 3.7 and 4.7 nM respectively). INCB 3284 also displays weak hERG activity; inhibits the hERG potassium current (IC50 = 84μM).
| Physical Appearance | A crystalline solid |
| Storage | Store at -20°C |
| M.Wt | 712.76 |
| Cas No. | 887401-93-6 |
| Formula | C28H39F3N4O10S2 |
| Synonyms | INCB-3284 dimesylate;INCB3284 dimesylate |
| Solubility | Soluble in DMSO |
| Chemical Name | N-(2-((1-(4-hydroxy-4-(6-methoxypyridin-3-yl)cyclohexyl)pyrrolidin-3-yl)amino)-2-oxoethyl)-3-(trifluoromethyl)benzamide dimethanesulfonate |
| SDF | Download SDF |
| Canonical SMILES | COC1=NC=C(C2(O)CCC(N3CCC(NC(CNC(C4=CC(C(F)(F)F)=CC=C4)=O)=O)C3)CC2)C=C1.CS(=O)(O)=O.CS(=O)(O)=O |
| 运输条件 | 蓝冰运输或根据您的需求运输。 |
| 一般建议 | 不同厂家不同批次产品溶解度各有差异，仅做参考。若实验所需浓度过大至产品溶解极限，请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存，请尽快用完。 |
