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HOAt

现货
Catalog No.
A7024
肽偶联剂
组合的产品项目
规格价格库存 数量
10mM (in 1mL DMSO)
¥ 500.00
现货
25g
¥ 770.00
现货
100g
¥ 1,920.00
现货

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Background

A coupling activator for racemization-free coupling in peptide synthesis; An additive for peptide segment coupling in in reducing the extent of configurational loss at the reactive carboxylic acid residue. Carpino L A etc. works demonstrated that the DIC/HOAt system is more effective in preserving configuration for peptide segment coupling than the analogous DIC/HOBt system

in DMF and DCM. [1]

Reference:
Carpino L A, El-Faham A.  The diisopropylcarbodiimide/1-hydroxy-7-azabenzotriazole system: segment coupling and stepwise peptide assembly[J]. Tetrahedron, 1999, 55(22): 6813-6830.

Chemical Properties

Physical AppearanceA solid
StorageDesiccate at -20°C
M.Wt136.11
Cas No.39968-33-7
FormulaC5H4N4O
Solubility≥6.8mg/mL in DMSO, ≥9.29 mg/mL in EtOH with ultrasonic, ≥3.62 mg/mL in H2O with ultrasonic
Chemical Name3-hydroxytriazolo[4,5-b]pyridine
SDFDownload SDF
Canonical SMILESC1=CC2=C(N=C1)N(N=N2)O
运输条件试用装:蓝冰运输。 其他可选规格:常温运输或根据您的要求用蓝冰运输。
一般建议为了使其更好的溶解,请用37℃加热试管并在超声波水浴中震动片刻。不同厂家不同批次产品溶解度各有差异,仅做参考。若实验所需浓度过大至产品溶解极限,请添加助溶剂助溶或自行调整浓度。

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