HOAt
mRNA synthesis
In vitro transcription of capped mRNA with modified nucleotides and Poly(A) tail
Tyramide Signal Amplification (TSA)
TSA (Tyramide Signal Amplification), used for signal amplification of ISH, IHC and IC etc.
Phos Binding Reagent Acrylamide
Separation of phosphorylated and non-phosphorylated proteins without phospho-specific antibody
Cell Counting Kit-8 (CCK-8)
A convenient and sensitive way for cell proliferation assay and cytotoxicity assay
SYBR Safe DNA Gel Stain
Safe and sensitive stain for visualization of DNA or RNA in agarose or acrylamide gels.
Inhibitor Cocktails
Protect the integrity of proteins from multiple proteases and phosphatases for different applications.
HOAt用于多肽合成中无消旋偶联的偶联激活剂,也是肽段偶联的添加剂,用于减少反应活性羧酸残基上构损失的程度。Carpino L A etc.的研究表明,与DMF和DCM中类似的DIC/HOBt系统相比,DIC/HOAt系统可以更加有效地保留用于肽段偶联的构造[1]。
参考文献:
1. Carpino L A, El-Faham A. The diisopropylcarbodiimide/1-hydroxy-7-azabenzotriazole system: segment coupling and stepwise peptide assembly[J]. Tetrahedron, 1999, 55(22): 6813-6830.
Physical Appearance | A solid |
Storage | Desiccate at -20°C |
M.Wt | 136.11 |
Cas No. | 39968-33-7 |
Formula | C5H4N4O |
Solubility | ≥3.62 mg/mL in H2O with ultrasonic; ≥6.81 mg/mL in DMSO; ≥9.29 mg/mL in EtOH with ultrasonic |
Chemical Name | 3-hydroxytriazolo[4,5-b]pyridine |
SDF | Download SDF |
Canonical SMILES | C1=CC2=C(N=C1)N(N=N2)O |
运输条件 | 蓝冰运输或根据您的需求运输。 |
一般建议 | 不同厂家不同批次产品溶解度各有差异,仅做参考。若实验所需浓度过大至产品溶解极限,请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存,请尽快用完。 |
质量控制和MSDS
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