Fusapyrone
mRNA synthesis
In vitro transcription of capped mRNA with modified nucleotides and Poly(A) tail
Tyramide Signal Amplification (TSA)
TSA (Tyramide Signal Amplification), used for signal amplification of ISH, IHC and IC etc.
Phos Binding Reagent Acrylamide
Separation of phosphorylated and non-phosphorylated proteins without phospho-specific antibody
Cell Counting Kit-8 (CCK-8)
A convenient and sensitive way for cell proliferation assay and cytotoxicity assay
SYBR Safe DNA Gel Stain
Safe and sensitive stain for visualization of DNA or RNA in agarose or acrylamide gels.
Inhibitor Cocktails
Protect the integrity of proteins from multiple proteases and phosphatases for different applications.
Fusapyrone, a broad-spectrum antifungal metabolite, is isolated from several Fusarium species.
Structurally, fusapyrone consists of a 4-deoxy-β-xylo-hexopyranosyl C-glycosyl moiety bound to the C-6 of the 2-pyrone ring and a highly functionalized aliphatic chain. Fusapyrone exhibited low zoo-toxicity, as evidenced by a lack of toxicity against Artemia salina. Fusapyrone exerted considerable antifungal activity against several plant mycotoxigenic, pathogenic, and human pathogenic filamentous fungi, including Aspergillus flavus, Aspergillus niger, Aspergillus parasiticus, and Aspergillus fumigatus [1]. Additionally, it had been investigated as a useful candidate for the control of postharvest crop diseases, including blocking the growth of ochratoxin-producing strains of Aspergillus section Nigri in wine grapes. However, fusapyrone was found to be ineffective toward yeasts isolated from fruits and plants and not toxic to Artemia salina (brine shrimp). The mechanism of action of fusapyrone is unknown and the structure of fusapyrone was revised in 2006.
In vitro: Up to now, in vitro study of fusapyrone is still in the development stage.
In vivo: Up to now, in vivo study of fusapyrone is still in the development stage.
Reference:
[1]. Favilla, M., Pascale, M., Ricelli, A., Evidente, A., Amalfitano, C., & Altomare, C. Inhibition of Species of the Aspergillus Section Nigri and Ochratoxin a Production in Grapes by Fusapyrone. Applied and Environmental Microbiology.2008; 74(7): 2248-2253.
Physical Appearance | A solid |
Storage | Store at -20°C |
M.Wt | 606.8 |
Cas No. | 156856-31-4 |
Formula | C34H54O9 |
Solubility | Soluble in DMSO |
Chemical Name | 3-(4-deoxy-β-xylo-hexopyranosyl)-2-hydroxy-6-[(3E,5E,8Z)-2-hydroxy-7-(hydroxymethyl)-1,1,5,9,11-pentamethyl-3,5,8-heptadecatrien-1-yl]-2H-pyran-2-one |
SDF | Download SDF |
Canonical SMILES | O[C@H]1C[C@@H](CO)O[C@@H](C2=C(O)OC(C(C)(C)C(O)/C=C/C(C)=C/C(CO)/C=C(C)\CC(C)CCCCCC)=CC2=O)[C@@H]1O |
运输条件 | 蓝冰运输或根据您的需求运输。 |
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