Fluconazole hydrate
mRNA synthesis
In vitro transcription of capped mRNA with modified nucleotides and Poly(A) tail
Tyramide Signal Amplification (TSA)
TSA (Tyramide Signal Amplification), used for signal amplification of ISH, IHC and IC etc.
Phos Binding Reagent Acrylamide
Separation of phosphorylated and non-phosphorylated proteins without phospho-specific antibody
Cell Counting Kit-8 (CCK-8)
A convenient and sensitive way for cell proliferation assay and cytotoxicity assay
SYBR Safe DNA Gel Stain
Safe and sensitive stain for visualization of DNA or RNA in agarose or acrylamide gels.
Inhibitor Cocktails
Protect the integrity of proteins from multiple proteases and phosphatases for different applications.
| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 324.29 |
| Cas No. | 155347-36-7 |
| Formula | C13H14F2N6O2 |
| Solubility | ≥16.35 mg/mL in DMSO; ≥28.8 mg/mL in EtOH; ≥3.2 mg/mL in H2O with ultrasonic |
| Chemical Name | 2-(2,4-difluorophenyl)-1,3-di(1H-1,2,4-triazol-1-yl)propan-2-ol hydrate |
| SDF | Download SDF |
| Canonical SMILES | FC1=CC(F)=C(C(CN2C=NC=N2)(O)CN3C=NC=N3)C=C1.O |
| 运输条件 | 蓝冰运输或根据您的需求运输。 |
| 一般建议 | 不同厂家不同批次产品溶解度各有差异，仅做参考。若实验所需浓度过大至产品溶解极限，请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存，请尽快用完。 |
| 细胞实验 [1]： | |
|
细胞系 |
致病性念珠菌属物种 |
|
溶解方法 |
在DMSO中的溶解度≥16.35mg/mL。为了获得更高的浓度，可以将离心管在37℃加热10分钟和/或在超声波浴中震荡一段时间。原液可以在-20℃以下储存几个月。 |
|
反应条件 |
100 mg / l |
|
应用 |
在标准真菌学培养基中进行的测试中，Fluconazole hydrate对致病性念珠菌的抑制浓度极低，通常超过100 mg / l。在低至10-6 M（0.3 mg / l）的浓度下，Fluconazole hydrate可抑制白色念珠菌的分支和菌丝发育，但在这些测试中，咪康唑和酮康唑的活性仍低于此浓度100倍。 |
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References: [1]. Odds FC, Cheesman SL, Abbott AB. Antifungal effects of fluconazole (UK 49858), a new triazole antifungal, in vitro. J Antimicrob Chemother. 1986 Oct;18(4):473-8. PubMed PMID: 3021710. |
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质量控制和MSDS
- 批次:
化学结构
