EZ Cap™ EGFP mRNA (5-moUTP)
Catalog No.
R1016
具有Cap 1结构的EGFP mRNA,使用5-moUTP修饰,提供更高的转录效率并抑制RNA介导的先天免疫激活。
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This product has EGFP mRNA with Cap 1 structure and contains 5-moUTP modification, which can provide higher transcription efficiency and inhibit RNA-mediated innate immune activation.
- 1. Yixuan Huang, Jiacai Wu, et al. "Quaternization drives spleen-to-lung tropism conversion for mRNA-loaded lipid-like nanoassemblies." Theranostics. 2024 Jan 1;14(2):830-842. PMID: 38169552
- 2. Mingzhu Gao, Maoping Tang, et al. "Modulating Plaque Inflammation via Targeted mRNA Nanoparticles for the Treatment of Atherosclerosis." ACS Nano. 2023 Sep 26;17(18):17721-17739. PMID: 37669404
- 3. Y. Huang, M. Yang, et al. "Intracellular delivery of messenger RNA to macrophages with surfactant-derived lipid nanoparticles." Materials Today Advances.
- 4. Min Li, Yixuan Huang, et al. "A PEG-lipid-free COVID-19 mRNA vaccine triggers robust immune responses in mice." Materials Horizons. PMID: 36468425
mRNA Length | 996 nucleotides | ||
Concentration | 1 mg/mL | ||
Buffer | 1 mM Sodium Citrate, pH 6.4 | Storage | -40°C or below |
General tips | 请将其于冰上溶解,并小心防止RNase污染降解。尽可能避免反复冻融。 不要涡旋震荡。首次使用时,将其轻柔离心并分成几份,可供单独使用。使用不含RNase的试剂和耗材,使用适当的无RNase技术。直至与转染试剂混合,才可加入含有血清的培养基中。 | ||
Shipping Condition | 试用装:干冰运输。 |