Enoxacin (Penetrex)
mRNA synthesis
In vitro transcription of capped mRNA with modified nucleotides and Poly(A) tail
Tyramide Signal Amplification (TSA)
TSA (Tyramide Signal Amplification), used for signal amplification of ISH, IHC and IC etc.
Phos Binding Reagent Acrylamide
Separation of phosphorylated and non-phosphorylated proteins without phospho-specific antibody
Cell Counting Kit-8 (CCK-8)
A convenient and sensitive way for cell proliferation assay and cytotoxicity assay
SYBR Safe DNA Gel Stain
Safe and sensitive stain for visualization of DNA or RNA in agarose or acrylamide gels.
Inhibitor Cocktails
Protect the integrity of proteins from multiple proteases and phosphatases for different applications.
Physical Appearance | A solid |
Storage | Store at -20°C |
M.Wt | 320.32 |
Cas No. | 74011-58-8 |
Formula | C15H17FN4O3 |
Solubility | insoluble in H2O; insoluble in EtOH; ≥18.4 mg/mL in DMSO |
Chemical Name | 1-ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,8-naphthyridine-3-carboxylic acid |
SDF | Download SDF |
Canonical SMILES | CCN1C=C(C(=O)C2=CC(=C(N=C21)N3CCNCC3)F)C(=O)O |
运输条件 | 蓝冰运输或根据您的需求运输。 |
一般建议 | 不同厂家不同批次产品溶解度各有差异,仅做参考。若实验所需浓度过大至产品溶解极限,请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存,请尽快用完。 |
细胞实验 [1]: | |
细胞系 |
人前列腺癌细胞系DU145、 LNCaP、VCaP和PC-3 |
溶解方法 |
在DMSO中的溶解度≥18.4mg。为了获得更高的浓度,可以将离心管在37℃加热10分钟和/或在超声波浴中震荡一段时间。原液可以在-20℃以下储存几个月。 |
反应条件 |
40 μg/ml |
应用 |
Enoxacin能够降低细胞活力,诱导细胞凋亡,引起细胞周期停滞,并抑制细胞系的侵袭性。Enoxacin在恢复miRNA的整体表达方面也很有效。 |
References: [1]. Sousa E, Graça I, Baptista T, Vieira FQ, Palmeira C, Henrique R, Jerónimo C. Enoxacin inhibits growth of prostate cancer cells and effectively restores microRNA processing. Epigenetics. 2013 May;8(5):548-58. doi: 10.4161/epi.24519. Epub 2013 Apr 17. PubMed PMID: 23644875; PubMed Central PMCID: PMC3741225. |
质量控制和MSDS
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