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DR 2313

 
Catalog No.
A4527
PARP抑制剂
组合的产品项目
规格价格库存 数量
1mg
¥ 650.00
Ship with 10-15 days
10mg
¥ 2,329.00
Ship with 10-15 days

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A

背景

Competitive inhibitor of poly(ADP-ribose) polymerase (PARP) (IC50 values are 0.20 and 0.24 μM for PARP-1 and PARP-2 respectively). Neuroprotective; reduces neuronal cell death in models of cerebral ischemia in vivo and in vitro. Brain penetrant.

化学属性

Physical AppearanceA crystalline solid
StorageStore at 4°C
M.Wt182.24
Cas No.284028-90-6
FormulaC8H10N2OS
Solubility≥83.33 mg/mL in DMSO; ≥9.1 mg/mL in H2O
Chemical Name2-methyl-1,5,7,8-tetrahydrothiopyrano[4,3-d]pyrimidin-4-one
SDFDownload SDF
Canonical SMILESCC1=NC(=O)C2=C(N1)CCSC2
运输条件 蓝冰运输或根据您的需求运输。
一般建议不同厂家不同批次产品溶解度各有差异,仅做参考。若实验所需浓度过大至产品溶解极限,请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存,请尽快用完。

生物活性

DR 2313 is a competitive inhibitor of PARP1 and PARP2 with IC50 of 0.20 and 0.24 μM respectively.
Targets PARPK1 PARP2        
IC50 0.20 μM 0.24 μM        

质量控制

质量控制和MSDS

批次:

化学结构

DR 2313