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DiscoveryProbe™ Tyrosine Kinase Inhibitor Library

 
Catalog No.
L1028
369个酪氨酸激酶抑制剂的独特集合,用于高通量筛选(HTS)和高含量筛选(HCS)。
组合的产品项目
规格价格库存 数量
100uL/well(10 mM solution),96 Well Deep Well Plate
¥ 41,500.00
现货
100uL/well(10 mM solution),96 Well Racks With Screw Cap
¥ 51,900.00
现货
250uL/well(10 mM solution),96 Well Racks With Screw Cap
¥ 92,600.00
现货

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Featured Products of the Library

Catalog No. Product Name Summary Targets CAS Number Smiles
A1389 WZ4002 Mutant-selective EGFR inhibitor(L858R,T790M), irreversible and potent EGFR 1213269-23-8 CN1CCN(CC1)C2=CC(=C(C=C2)NC3=NC=C(C(=N3)OC4=CC=CC(=C4)NC(=O)C=C)Cl)OC
A2838 OSI-930 Inhibitor of Kit, KDR, Flt, CSF-1R, c-Raf and Lck c-Kit 728033-96-3 C1=CC=C2C(=C1)C(=CC=N2)CNC3=C(SC=C3)C(=O)NC4=CC=C(C=C4)OC(F)(F)F
A3014 BGJ398 FGFR inhibitor ,potent and selective FGFR 872511-34-7 CCN1CCN(CC1)C2=CC=C(C=C2)NC3=CC(=NC=N3)N(C)C(=O)NC4=C(C(=CC(=C4Cl)OC)OC)Cl
A5092 JNJ-38877605 C-Met inhibitor,ATP-competitive c-MET 943540-75-8 CN1C=C(C=N1)C2=NN3C(=NN=C3C(C4=CC5=C(C=C4)N=CC=C5)(F)F)C=C2
A8324 LDN-193189 ALK inhibitor,potent and selective SMAD 1062368-24-4 C1CN(CCN1)C2=CC=C(C=C2)C3=CN4C(=C(C=N4)C5=CC=NC6=CC=CC=C56)N=C3
A8329 R428 Selective Axl inhibitor Axl 1037624-75-1 C1CCN(C1)C2CCC3=C(CC2)C=C(C=C3)NC4=NN(C(=N4)N)C5=NN=C6C(=C5)CCCC7=CC=CC=C76
A8528 TAK-285 HER2/EGFR(HER1) inhibitor HER2 871026-44-7 CC(C)(CC(=O)NCCN1C=CC2=C1C(=NC=N2)NC3=CC(=C(C=C3)OC4=CC=CC(=C4)C(F)(F)F)Cl)O
A8696 FIIN-2 Irreversible inhibitor of FGFR EGFR 1633044-56-0 O=C(C=C)NC1=CC=C(CN2C(N(C3=CC(OC)=CC(OC)=C3)CC4=CN=C(NC5=CC=C(N6CCN(C)CC6)C=C5)N=C42)=O)C=C1
下载 APExBIO化合物库使用说明
下载 DiscoveryProbe™ Tyrosine Kinase Inhibitor Library(SDF & XLSX)

质量控制

相关生物数据

GSK1904529A

相关生物数据

GSK1904529A

相关生物数据

R428

相关生物数据

R428

相关生物数据

Bafetinib
 

Signaling Pathway

Bcr-Abl Compare Products
PKC Compare Products
ROCK Compare Products
 

Storage and Shipping Information

Form Pre-dissolved DMSO solutions Stability Solution: -20°C for 12 months, -80°C for 24 months
Packaging 96-well DeepWell format with peelable foil seal and EVA cap (100 μL/well, 10 mM DMSO).
96-well rack with Matrix 2D Barcoded ScrewTop Storage tubes (250 μL or 100 μL/well, 10 mM DMSO).
Shipping Condition Evaluation sample solution: ship with blue ice
All other available size: ship with RT, or blue ice upon request

Compound Library Composition

Advantages

-- Available in stock with overnight delivery and free shipping over $500.

-- Cost-effective and competitive price to save your budget.

-- Potent, selective and cell-permeable in inhibiting or activating target molecules.

-- Diverse in chemical structure and route of administration (oral/i.m/i.v injection etc.)

-- Detailed files describing potency, selectivity and applications etc.

-- Supported by published data from top peer-reviewed journals.

-- Guaranteed high quality with NMR and HPLC validation.