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Cy7 carboxylic acid (non-sulfonated)

 
Catalog No.
A8135
非反应性荧光团,用于对照实验和校准
组合的产品项目
规格价格库存 数量
5mg
¥ 5,405.00
现货
25mg
¥ 10,553.00
Ship with 10-15 days

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A

背景

Cy7 carboxylic acid is a near-infrared fluorescent dye which has low aqueous solubility. As for coupling and labeling reactions, pre-activated Cy7 NHS ester or water-soluble sulfo-Cy7 NHS ester would be considered. For biomolecule labeling, the labeling reagent has low aqueous solubility, using of organic co-solvent to dissolve this molecular is necessary for efficient reaction. First, Cyanine dye should be dissolved in organic solvent and then added to a solution of biomolecule in appropriate aqueous buffer.

Cy7, together with carboxylic acid (CA) make up the model drugs. On the basis of this, the study was able to estimate the amount of Cy7 carboxylic acid on the particle through direct emission spectra measurements [1].

Reference:
[1] Zhao, Y. ; Fay, F.; Hak, S.; Manuel Perez-Aguilar, J.; Sanchez-Gaytan, B.L.; Goode, B.; Duivenvoorden, R.; de Lange Davies, C.; Bjrky, A.; Weinstein, H.; Fayad, Z.A.; Pérez-Medina, C.; Mulder, W.J.M. Augmenting drug-carrier compatibility improves tumour nanotherapy efficacy. Nature Communications, 2016,7,11221.

化学属性

Storage24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
M.Wt585.22
FormulaC37H45ClN2O2
Solubilitysoluble in organic solvents (DMSO, DMF, dichloromethane), low solubility in water
Chemical Name6-[(2E)-3,3-dimethyl-2-[(2E)-2-[3-[(E)-2-(1,3,3-trimethylindol-1-ium-2-yl)ethenyl]cyclohex-2-en-1-ylidene]ethylidene]indol-1-yl]hexanoic acid
SDFDownload SDF
Canonical SMILESCC1(C2=CC=CC=C2[N+](=C1C=CC3=CC(=CC=C4C(C5=CC=CC=C5N4CCCCCC(=O)O)(C)C)CCC3)C)C
运输条件 蓝冰运输或根据您的需求运输。
一般建议不同厂家不同批次产品溶解度各有差异,仅做参考。若实验所需浓度过大至产品溶解极限,请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存,请尽快用完。

Spectral properties

最大激发光波 (nm) 750 最大发射光波 (nm) 773
消光系数 (M-1cm-1) 199000 量子产量 N/A
CF260 0.022 CF280 0.029

质量控制

质量控制和MSDS

批次:

化学结构

Cy7 carboxylic acid (non-sulfonated)

相关生物数据

Cy7 carboxylic acid (non-sulfonated)