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Cy5.5 carboxylic acid (non-sulfonated)

 
Catalog No.
A8134
非反应性荧光团,用于对照实验和校准
组合的产品项目
规格价格库存 数量
5mg
¥ 2,275.00
现货
25mg
¥ 4,441.00
现货

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A

背景

Cy5.5 carboxylic acid is an un-activated labeling regent which has low aqueous solubility. For biomolecule labeling, the labeling reagent has low aqueous solubility, using of organic co-solvent to dissolve this molecular is necessary for efficient reaction. First, Cyanine dye should be dissolved in organic solvent and then added to a solution of biomolecule in appropriate aqueous buffer.

Cyanine 5.5 carboxylic acid instead of the drug was injected into the tumors in order to visually observe the dye release by using the in vivo imaging system (IVIS). Research show that NIR irradiation could efficiently triggered drug release from the DEPt-PEG/α-CD hydrogel in vivo [1].

Reference:
[1] Wang, X. ; Wang, C.; Zhang, Q.; Cheng, Y. Near Infrared Light-responsive and Injectable Supramolecular Hydrogels for On-demand Drug Delivery. Chemical Communications, 2016, 52, 978–981.

化学属性

Physical AppearanceA solid
Storage24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
M.Wt619.23
FormulaC40H43ClN2O2
Solubilityinsoluble in H2O; ≥16.73 mg/mL in EtOH with ultrasonic; ≥213 mg/mL in DMSO
Chemical Name6-[(2E)-1,1-dimethyl-2-[(2E,4E)-5-(1,1,3-trimethylbenzo[e]indol-3-ium-2-yl)penta-2,4-dienylidene]benzo[e]indol-3-yl]hexanoic acid
SDFDownload SDF
Canonical SMILESCC1(C(=[N+](C2=C1C3=CC=CC=C3C=C2)C)C=CC=CC=C4C(C5=C(N4CCCCCC(=O)O)C=CC6=CC=CC=C65)(C)C)C
运输条件 蓝冰运输或根据您的需求运输。
一般建议不同厂家不同批次产品溶解度各有差异,仅做参考。若实验所需浓度过大至产品溶解极限,请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存,请尽快用完。

Spectral properties

最大激发光波 (nm) 684 最大发射光波 (nm) 710
消光系数 (M-1cm-1) 209000 量子产量 0.2
CF260 0.07 CF280 0.03

质量控制

化学结构

Cy5.5 carboxylic acid (non-sulfonated)

相关生物数据

Cy5.5 carboxylic acid (non-sulfonated)