Cefadroxil (hydrate)
mRNA synthesis
In vitro transcription of capped mRNA with modified nucleotides and Poly(A) tail
Tyramide Signal Amplification (TSA)
TSA (Tyramide Signal Amplification), used for signal amplification of ISH, IHC and IC etc.
Phos Binding Reagent Acrylamide
Separation of phosphorylated and non-phosphorylated proteins without phospho-specific antibody
Cell Counting Kit-8 (CCK-8)
A convenient and sensitive way for cell proliferation assay and cytotoxicity assay
SYBR Safe DNA Gel Stain
Safe and sensitive stain for visualization of DNA or RNA in agarose or acrylamide gels.
Inhibitor Cocktails
Protect the integrity of proteins from multiple proteases and phosphatases for different applications.
Cefadroxil is a new semisynthetic cephalosporin with a broad antibacterial spectrum and a high chemotherapeutic potential [1].
In vitro: The inhibitory activity of this compound was similar to that of cephalexin and cephradine when tested against 602 clinical isolates on Mueller-Hinton medium. In the oral treatment of experimental infections of mice, cefadroxil was more effective than cephalexin against Streptococcus pyogenes, and comparably effective against Streptococcus pneumoniae, Staphylococcus aureus, and several gram-negative species [1].
In vivo: In mice, oral administration of cefadroxil at doses ranging from 25 to 100 mg/kg attained peak concentrations in the blood. Higher peak levels were noted with cefadroxil than with cephalexin at a dose of 200 mg/kg [1].
Clinical trials: A single daily dose of cefadroxil appeared to be as effective in the treatment of patients with A β-hemolytic streptococcal (GABHS) pharyngitis [2].
References:
[1] Buck R E, Price K E. Cefadroxil, a new broad-spectrum cephalosporin[J]. Antimicrobial agents and chemotherapy, 1977, 11(2): 324-330.
[2] Gerber M A, Randolph M F, Chanatry J, et al. Once daily therapy for streptococcal pharyngitis with cefadroxil[J]. The Journal of pediatrics, 1986, 109(3): 531-537.
Storage | Store at -20°C |
M.Wt | 381.4 |
Cas No. | 66592-87-8 |
Formula | C16H17N3O5S·H2O |
Synonyms | Duricef,Bidocel |
Solubility | insoluble in EtOH; insoluble in H2O; ≥5.8 mg/mL in DMSO with gentle warming |
Chemical Name | (6R,7R)-7-[[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, monohydrate |
SDF | Download SDF |
Canonical SMILES | OC1=CC=C([C@@H](N)C(N[C@@H]2C(N3[C@]2([H])SCC(C)=C3C(O)=O)=O)=O)C=C1.O |
运输条件 | 蓝冰运输或根据您的需求运输。 |
一般建议 | 不同厂家不同批次产品溶解度各有差异,仅做参考。若实验所需浓度过大至产品溶解极限,请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存,请尽快用完。 |
质量控制和MSDS
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