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6α-methyl-11β-Hydroxyprogesterone

甲羟松
Catalog No.
C4050
皮质类固醇和抗炎
组合的产品项目
规格价格库存 数量
250mg
¥ 1,625.00
Ship with 10-15 days

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背景

6α-Methyl-11β-hydroxyprogesterone is a synthetic glucocorticoid which has been used in the treatment of inflammatory eye diseases. 6α-Methyl-11β-hydroxyprogesterone is a corticosteroid with anti-inflammatory properties which has been discontinued in the United States. The structure of 6α-Methyl-11β-hydroxyprogesterone is very similar to progesterone. Neither progestogenic nor androgenic activity has been demonstrated for or attributed to medrysone [1, 2].

References:
[1] The dictionary of drugs: chemical data: chemical data, structures and bibliographies[M].  Springer, 2014.
[2] SPAETH G L.  Hydroxymethylprogesterone: An anti-inflammatory steroid without apparent effect on intraocular pressure[J]. Archives of Ophthalmology, 1966, 75(6): 783-787.

化学属性

Physical AppearanceA crystalline solid
StorageStore at -20°C
M.Wt344.5
Cas No.2668-66-8
FormulaC22H32O3
SynonymsNSC 63278,Visudrisone
Solubility≤1mg/ml in ethanol;1mg/ml in methanol;1mg/ml in acetonitrile
Chemical Name(6α,11β)-11-hydroxy-6-methyl-pregn-4-ene-3,20-dione
SDFDownload SDF
Canonical SMILESC[C@@]12[C@](CC[C@@H]2C(C)=O)([H])[C@]3([H])C[C@H](C)C4=CC(CC[C@]4(C)[C@@]3([H])[C@@H](O)C1)=O
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化学结构

6α-methyl-11β-Hydroxyprogesterone