Heparin sodium
mRNA synthesis
In vitro transcription of capped mRNA with modified nucleotides and Poly(A) tail
Tyramide Signal Amplification (TSA)
TSA (Tyramide Signal Amplification), used for signal amplification of ISH, IHC and IC etc.
Phos Binding Reagent Acrylamide
Separation of phosphorylated and non-phosphorylated proteins without phospho-specific antibody
Cell Counting Kit-8 (CCK-8)
A convenient and sensitive way for cell proliferation assay and cytotoxicity assay
SYBR Safe DNA Gel Stain
Safe and sensitive stain for visualization of DNA or RNA in agarose or acrylamide gels.
Inhibitor Cocktails
Protect the integrity of proteins from multiple proteases and phosphatases for different applications.
| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 50000 |
| Cas No. | 9041-08-1 |
| Solubility | insoluble in EtOH; insoluble in DMSO; ≥12.75 mg/mL in H2O |
| 运输条件 | 蓝冰运输或根据您的需求运输。 |
| 一般建议 | 不同厂家不同批次产品溶解度各有差异，仅做参考。若实验所需浓度过大至产品溶解极限，请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存，请尽快用完。 |
| Animal experiment:[1] | |
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Animal models |
Male New Zealand rabbits with a mean body weight of 2300 ± 300 g |
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Dosage form |
2000 IU heparin Administered by the intravenous route (i.v.) |
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Applications |
Heparin increased both anti-factor Xa activity and activated partial thromboplastin time (aPTT). Heparin (2000 IU, i.v.) showed an AUC0→24/kg value of 3.30 ± 0.59 IU·h-1·mL-1·kg-1, with 100% absolute bioavailability. Apart from the parenteral route, heparin could also be administered by the oral route when incorporated into polymeric nanoparticles which were able to maintain the anti-Xa activity of heparin for a longer period. |
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Note |
The technical data provided above is for reference only. |
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References: 1. Jiao Y, Ubrich N, Marchand-Arvier M, et al. In vitro and in vivo evaluation of oral heparin-loaded polymeric nanoparticles in rabbits. Circulation, 2002, 105(2): 230-235. |
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