Glycoprotein B (485-492)
mRNA synthesis
In vitro transcription of capped mRNA with modified nucleotides and Poly(A) tail
Tyramide Signal Amplification (TSA)
TSA (Tyramide Signal Amplification), used for signal amplification of ISH, IHC and IC etc.
Phos Binding Reagent Acrylamide
Separation of phosphorylated and non-phosphorylated proteins without phospho-specific antibody
Cell Counting Kit-8 (CCK-8)
A convenient and sensitive way for cell proliferation assay and cytotoxicity assay
SYBR Safe DNA Gel Stain
Safe and sensitive stain for visualization of DNA or RNA in agarose or acrylamide gels.
Inhibitor Cocktails
Protect the integrity of proteins from multiple proteases and phosphatases for different applications.
糖蛋白B（485-492）的化学式为C41H67N11O13，氨基酸序列为H2N-Ser-Ser-Ile-Glu-Phe-Ala-Arg-Leu-OH，分子量为922.04。糖蛋白B是一种病毒糖蛋白，参与单纯疱疹病毒（HSV）进入细胞的过程。疱疹病毒含有一个包被和一个外脂质双层，其中包含12个表面糖蛋白。单纯疱疹病毒包被与细胞膜融合，经过内吞作用，双链DNA基因组进入宿主细胞，产生感染(1)。疱疹病毒糖蛋白B是所有细胞膜糖蛋白中最高度保守的，主要作为融合蛋白。gB和gH/ gL的精确功能未知，但它们对于病毒进入细胞是必须的，构成核心融合单位。糖蛋白B的胞质域内的某些突变引起显著的合胞体表型(2)，且与其它病毒融合蛋白具有结构同源性，由此认为gB参与了融合过程(3)。
Figure1 the structures of Glycoprotein B
Figure 2 mechanism of virus into cells
参考文献：
1. PereiraL, Ali M, Kousoulas K, Huo B, Banks T (September 1989). "Domain structure of herpes simplex virus 1 glycoprotein B: neutralizing epitopes map in regions of continuous and discontinuous residues". Virology 172 (1): 11–24.
2. Bender FC, Samanta M, Heldwein EE, de Leon MP, Bilman E, Lou H, Whitbeck JC, Eisenberg RJ, Cohen GH (April 2007). "Antigenic and mutational analyses of herpes simplex virus glycoprotein B reveal four functional regions". J. Virol. 81 (8): 3827–41.
3. Heldwein EE, Lou H, Bender FC, Cohen GH, Eisenberg RJ, Harrison SC (July 2006). "Crystalstructure of glycoprotein B from herpes simplex virus 1". Science 313 (5784): 217–20.
| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 922.04 |
| Formula | C41H67N11O13 |
| Synonyms | H2N-Ser-Ser-Ile-Glu-Phe-Ala-Arg-Leu-OH |
| Solubility | ≥92.2 mg/mL in DMSO; insoluble in EtOH; ≥12.24 mg/mL in H2O |
| SDF | Download SDF |
| Canonical SMILES | NC(CO)C(NC(CO)C(NC(C(CC)C)C(NC(CCC(O)=O)C(NC(CC1=CC=CC=C1)C(NC(C)C(NC(CCCNC(N)=N)C(NC(CC(C)C)C(O)=O)=O)=O)=O)=O)=O)=O)=O |
| 运输条件 | 蓝冰运输或根据您的需求运输。 |
| 一般建议 | 不同厂家不同批次产品溶解度各有差异，仅做参考。若实验所需浓度过大至产品溶解极限，请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存，请尽快用完。 |
质量控制和MSDS
- 批次:
化学结构
