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Schaftoside

现货
Catalog No.
N2082
天然产物
组合的产品项目
规格价格库存 数量
10mM (in 1mL DMSO)
¥ 2,000.00
现货
20mg
¥ 4,500.00
现货

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Background

Schaftosideextracted from rice phloem can be usedas feeding inhibitors and resistance factors to brown planthoppers,Nilaparvatalugens[1].The screening of several Chinese medicinal herbs for nematicidal properties has shown thatArisaemaerubescens(Wall.) Schott tubers possessed significant nematicidal activity against the root-knot nematode (Meloidogyne incognita). Two nematicidal flavone-C-glycosides were isolated by bioassay-guided fractionation from the ethanol extract. on the basis of their phytochemical and spectral data, the compounds were identified as schaftoside and isoschaftoside. Schaftoside and isoschaftosideexihibited strong nematicidal activity againstM.incognitawith the LC50values of 114.66 μg/mL and 323.09 μg/mL, respectively, the crude extract ofA.erubescensexhibited nematicidal activity against the root-knot nematode with a LC50value of 258.11 μg/mL[2].

References:
[1]. Stevenson P C, Kimmins F M, Grayer R J, et al. Schaftosides from rice phloem as feeding inhibitors and resistance factors to brown planthoppers, Nilaparvatalugens[J]. EntomologiaExperimentalisetApplicata, 1996, 80(1): 246-249.
[2]. Du S S, Zhang H M, Bai C Q, et al. Nematocidal flavone-C-glycosides against the root-knot nematode (Meloidogyne incognita) from Arisaemaerubescens tubers[J]. Molecules, 2011, 16(6): 5079-5086.

Chemical Properties

StorageStore at -20°C
M.Wt564.49
Cas No.51938-32-0
FormulaC26H28O14
Solubility≥50mg/mL in DMSO, ≥50mg/mL in MeOH
Chemical Name5,7-dihydroxy-2-(4-hydroxyphenyl)-6-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-8-[(2S,3R,4S,5S)-3,4,5-trihydroxyoxan-2-yl]chromen-4-one
SDFDownload SDF
Canonical SMILESC1C(C(C(C(O1)C2=C(C(=C(C3=C2OC(=CC3=O)C4=CC=C(C=C4)O)O)C5C(C(C(C(O5)CO)O)O)O)O)O)O)O
运输条件试用装:蓝冰运输。 其他可选规格:常温运输或根据您的要求用蓝冰运输。
一般建议为了使其更好的溶解,请用37℃加热试管并在超声波水浴中震动片刻。不同厂家不同批次产品溶解度各有差异,仅做参考。若实验所需浓度过大至产品溶解极限,请添加助溶剂助溶或自行调整浓度。

试验操作

细胞实验 [1]:

细胞系

南方根结线虫,天南星

溶解方法

该化合物在DMSO中的溶解度大于16.3 mg/mL。若获取更高浓度的溶液,可在37℃下孵育10分钟,随后在超声波浴中摇匀。-20℃以下可储存数月。

反应条件

72 h

应用

Schaftoside对南方根结线虫具有强烈的杀线虫活性,LC50为114.66 μg/mL。Schaftoside对天南星粗提取物显示强烈的杀线虫活性,对根结线虫具有杀线虫活性,LC50值为258.11 μg/mL。

注意事项

由于实验环境的不同,实际溶解度可能与理论值略有不同,请测试室内所有化合物的溶解度。

References:

[1]. Du, Shu Shan, et al. "Nematocidal flavone-C-glycosides against the root-knot nematode (Meloidogyne incognita) from Arisaema erubescens tubers." Molecules 16.6 (2011): 5079-5086.

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