β-Interleukin II (44-56)
mRNA synthesis
In vitro transcription of capped mRNA with modified nucleotides and Poly(A) tail
Tyramide Signal Amplification (TSA)
TSA (Tyramide Signal Amplification), used for signal amplification of ISH, IHC and IC etc.
Phos Binding Reagent Acrylamide
Separation of phosphorylated and non-phosphorylated proteins without phospho-specific antibody
Cell Counting Kit-8 (CCK-8)
A convenient and sensitive way for cell proliferation assay and cytotoxicity assay
SYBR Safe DNA Gel Stain
Safe and sensitive stain for visualization of DNA or RNA in agarose or acrylamide gels.
Inhibitor Cocktails
Protect the integrity of proteins from multiple proteases and phosphatases for different applications.
β-白细胞介素II（44-56），分子式为C68H113N19O19，序列为NH2-ILE-LEU-ASN-GLY-ILE-ASN-ASN-TYR-LYS-ASN-PRO-LYS-LEU-COOH，分子量为1500.7。白细胞介素-2（IL-2）属于白细胞介素家族，是免疫系统的细胞因子信号分子，参与调节免疫系统白细胞的活性。IL-2是免疫系统的可溶性激素样调节剂，是鉴定到的第一个白介素分子，参与T细胞的生长、增殖和分化，促进T细胞形成“效应子”T细胞。IL-2是在免疫应答过程中由T细胞产生的，对于T细胞免疫记忆的发展是必须的，这取决于抗原选择性T细胞数目和功能的扩展。在胸腺的T细胞的发育中，IL-2对于T细胞的成熟是必须的，又被称为调节性T细胞。
Figure1 Formula of b-Interleukin II (44-56)
Figure2 Structure of Interleukin II
参考文献：
1. Cantrell DA, Smith KA (June 1984). "The interleukin-2 T-cell system: a new cell growth model". Science 224 (4655): 1312–6.
2. Smith KA (May 1988). "Interleukin-2: inception, impact, and implications". Science 240 (4856): 1169–76.
3. Sakaguchi S, Sakaguchi N, Asano M, Itoh M, Toda M (August 1995). "Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases". J. Immunol. 155 (3): 1151–64.
4. ThorntonAM, Shevach EM (July 1998). "CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production". J. Exp. Med. 188 (2): 287–96.
| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 1500.74 |
| Formula | C68H113N19O19 |
| Synonyms | H2N-Ile-Leu-Asn-Gly-Ile-Asn-Asn-Tyr-Lys-Asn-Pro-Lys-Leu-OH |
| Solubility | insoluble in EtOH; ≥150 mg/mL in DMSO; ≥26.25 mg/mL in H2O |
| SDF | Download SDF |
| Canonical SMILES | C[C@@H](CC)[C@H](N)C(N[C@H](CC(C)C)C(N[C@H](CC(N)=O)C(NCC(N[C@H]([C@@H](CC)C)C(N[C@H](CC(N)=O)C(N[C@H](CC(N)=O)C(N[C@H](CC1=CC=C(O)C=C1)C(N[C@H](CCCCN)C(N[C@H](CC(N)=O)C(N2CCC[C@H]2C(N[C@H](CCCCN)C(N[C@H](CC(C)C)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O |
| 运输条件 | 蓝冰运输或根据您的需求运输。 |
| 一般建议 | 不同厂家不同批次产品溶解度各有差异，仅做参考。若实验所需浓度过大至产品溶解极限，请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存，请尽快用完。 |
质量控制和MSDS
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化学结构
