Avermectin B1
mRNA synthesis
In vitro transcription of capped mRNA with modified nucleotides and Poly(A) tail
Tyramide Signal Amplification (TSA)
TSA (Tyramide Signal Amplification), used for signal amplification of ISH, IHC and IC etc.
Phos Binding Reagent Acrylamide
Separation of phosphorylated and non-phosphorylated proteins without phospho-specific antibody
Cell Counting Kit-8 (CCK-8)
A convenient and sensitive way for cell proliferation assay and cytotoxicity assay
SYBR Safe DNA Gel Stain
Safe and sensitive stain for visualization of DNA or RNA in agarose or acrylamide gels.
Inhibitor Cocktails
Protect the integrity of proteins from multiple proteases and phosphatases for different applications.
| Physical Appearance | A crystalline solid |
| Storage | Store at -20°C |
| M.Wt | 873.08 |
| Cas No. | 71751-41-2 |
| Formula | C48H72O14 |
| Synonyms | Abamectin; Avermectin B1a-Avermectin B1b mixt. |
| Solubility | Soluble in DMSO |
| SDF | Download SDF |
| Canonical SMILES | CCC(C1C(C)C=CC2(CC3CC(C/C=C(C)/C(OC4CC(OC)C(OC5CC(OC)C(O)C(C)O5)C(C)O4)C(C)/C=C/C=C6COC7C\6(O)C(C(O3)=O)C=C(C)C7O)O2)O1)C |
| 运输条件 | 蓝冰运输或根据您的需求运输。 |
| 一般建议 | 不同厂家不同批次产品溶解度各有差异，仅做参考。若实验所需浓度过大至产品溶解极限，请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存，请尽快用完。 |
| 动物实验 [1]： | |
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动物模型 |
马和矮种马 |
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剂量 |
0.2 mg/kg（p.o.） |
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应用 |
Avermectin B1治疗后导致第14、28和42天平均菌丝卵数显着下降。这种avermectin B1制剂的口服给药似乎对肠道菌群和盘尾属微丝蚴非常有效。但是，抗卵磷脂活性的持续时间比ivermectin糊剂的持续时间短得多。 |
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注意事项 |
请测试所有化合物在室内的溶解度，实际溶解度和理论值可能略有不同，这是由实验系统的误差引起的，属于正常现象。 |
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References: [1]. Mogg TD, Pollitt CC, Willmore JP, Thompson H. Efficacy of avermectin B1 given orally against equine intestinal strongyles and Onchocera microfilaria. Aust Vet J. 1990 Nov;67(11):399-401. doi: 10.1111/j.1751-0813.1990.tb03026.x. PMID: 2085293. |
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