Asenapine hydrochloride
阿塞那平盐酸盐
Catalog No.
A3192
非典型抗精神病药
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Asenapine is a new atypical antipsychotic developed for the treatment of schizophrenia and acute mania associated with bipolar disorder. Asenapine shows high affinity (pKi) for numerous receptors, including the serotonin 5-HT1A (8.6), 5-HT1B (8.4), 5-HT2A (10.2), 5-HT2B (9.8), 5-HT2C (10.5), 5-HT5A (8.8), 5-HT6 (9.5), and 5-HT7 (9.9) receptors, the adrenergic α1 (8.9), α2A (8.9), α2B (9.5), and α2C (8.9) receptors, the dopamine D1 (8.9), D2 (8.9), D3 (9.4), and D4 (9.0) receptors, and the histamine H1 (9.0) and H2 (8.2) receptors. Asenapine behaves as an antagonist at all receptors.
| Storage | Store at -20°C |
| M.Wt | 322.23 |
| Cas No. | 1412458-61-7 |
| Formula | C17H17Cl2NO |
| Synonyms | Saphris hydrochloride |
| Solubility | Soluble in DMSO |
| Chemical Name | (3aS,12bS)-5-chloro-2-methyl-2,3,3a,12b-tetrahydro-1H-dibenzo[2,3:6,7]oxepino[4,5-c]pyrrole hydrochloride |
| SDF | Download SDF |
| Canonical SMILES | ClC1=C([H])C2=C(C([H])=C1[H])OC3=C([H])C([H])=C([H])C([H])=C3[C@]4([H])[C@]2([H])C([H])([H])N(C([H])([H])[H])C4([H])[H].Cl[H] |
| 运输条件 | 蓝冰运输或根据您的需求运输。 |
| 一般建议 | 不同厂家不同批次产品溶解度各有差异，仅做参考。若实验所需浓度过大至产品溶解极限，请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存，请尽快用完。 |
化学结构
