ANP (1-11), rat
mRNA synthesis
In vitro transcription of capped mRNA with modified nucleotides and Poly(A) tail
Tyramide Signal Amplification (TSA)
TSA (Tyramide Signal Amplification), used for signal amplification of ISH, IHC and IC etc.
Phos Binding Reagent Acrylamide
Separation of phosphorylated and non-phosphorylated proteins without phospho-specific antibody
Cell Counting Kit-8 (CCK-8)
A convenient and sensitive way for cell proliferation assay and cytotoxicity assay
SYBR Safe DNA Gel Stain
Safe and sensitive stain for visualization of DNA or RNA in agarose or acrylamide gels.
Inhibitor Cocktails
Protect the integrity of proteins from multiple proteases and phosphatases for different applications.
心钠素(ANP)的化学式为C49H84N20O15S,氨基酸序列为H-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-OH,是一个含有28个氨基酸的多肽,由心房肌细胞合成、存储和释放,心房肌细胞响应心房扩张、血管紧张素II刺激、内皮素和交感神经刺激释放ANP。 ANP是一个功能强大的血管扩张剂,是心脏肌肉细胞分泌的蛋白质(多肽)激素,它参与体内水、钠、钾和脂肪组织的稳态控制。高血压条件下,心脏(心房肌细胞)中的上腔室(心房)的肌肉细胞释放ANP。ANP可以减少循环系统的水、钠和脂肪负载,从而降低血压。
参考文献:
1. Widmaier, Eric P.; Hershel Raff, Kevin T. Strang (2008). Vander's Human Physiology, 11th Ed.. McGraw-Hill. pp. 291, 509–10.
2. Marieb Human Anatomy & Physiology 9th edition, chapter:16, page:629, question number:14
3. de Bold A (1985). "Atrial natriuretic factor: a hormone produced by the heart". Science 230 (4727): 767–70.
Physical Appearance | A solid |
Storage | Store at -20°C |
M.Wt | 1225.38 |
Formula | C49H84N20O15S |
Synonyms | H2N-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-OH |
Solubility | ≥122.5 mg/mL in DMSO; insoluble in EtOH; ≥43.5 mg/mL in H2O |
SDF | Download SDF |
Canonical SMILES | N[C@@H](CO)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CO)C(N[C@@H](CO)C(N[C@@H](CS)C(N[C@@H](CC1=CC=CC=C1)C(NCC(NCC(N[C@@H](CCCNC(N)=N)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O |
运输条件 | 蓝冰运输或根据您的需求运输。 |
一般建议 | 不同厂家不同批次产品溶解度各有差异,仅做参考。若实验所需浓度过大至产品溶解极限,请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存,请尽快用完。 |
质量控制和MSDS
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