Angiotensin III (human, mouse)
mRNA synthesis
In vitro transcription of capped mRNA with modified nucleotides and Poly(A) tail
Tyramide Signal Amplification (TSA)
TSA (Tyramide Signal Amplification), used for signal amplification of ISH, IHC and IC etc.
Phos Binding Reagent Acrylamide
Separation of phosphorylated and non-phosphorylated proteins without phospho-specific antibody
Cell Counting Kit-8 (CCK-8)
A convenient and sensitive way for cell proliferation assay and cytotoxicity assay
SYBR Safe DNA Gel Stain
Safe and sensitive stain for visualization of DNA or RNA in agarose or acrylamide gels.
Inhibitor Cocktails
Protect the integrity of proteins from multiple proteases and phosphatases for different applications.
血管紧张素III (Asp | Arg-Val-Tyr-Ile-His-Pro-Phe)是一个六肽，在红细胞和大多数组织血管床的血管紧张素酶的作用下，血管紧张素Ⅱ的N-末端裂解形成血管紧张素III，而血管紧张素Ⅱ在肾素-血管紧张素-醛固酮系统 (Renin-Angiotensin-Aldosterone， RAAS)中发挥关键作用。血管紧张素III具有40％血管紧张素II的压力活性以及100％的醛固酮产生活性。
在外周血管紧张素系统中，血管紧张素II是体循环中的主要效应肽，外源血管紧张素III与血管紧张素Ⅱ效果相当，例如，刺激醛固酮分泌[1]或抑制肾素释放[2]。在大鼠脑中，作为一种升压药或致渴剂，血管紧张素III与血管紧张素II效果相当[3]，与血管紧张素II一样对神经系统有较强的结合。血管紧张素受体亚型AT1对血管紧张素Ⅱ有较大的亲和力，也可响应血管紧张素III，而AT2受体亚型似乎对血管紧张素III更敏感，较少响应于血管紧张素Ⅱ[4]。
Fig. 1: Formula of Angiotensin III
Fig. 2: Hypothesized interaction of each prominent brain angiotensin with its binding site.
参考文献：
1. Blair-West, JR. et al. (1980) J. Endocrinol. 87, 409.
2. Fei, DTW. et al. (1980) Life Sci. 27, 1495.
3. Fink, GD. et al. (1985) Am. J. Physiol. Endocrinol. Metab. 249, E201.
4. Wright, JW. et al. (2011) Prog. Neurobiol. 95, 49.
| Physical Appearance | A solid |
| Storage | Desiccate at -20°C |
| M.Wt | 931.09 |
| Cas No. | 13602-53-4 |
| Formula | C46H66N12O9 |
| Synonyms | Arg-Val-Tyr-Ile-His-Pro-Phe |
| Solubility | ≥23.2 mg/mL in H2O; ≥43.8 mg/mL in EtOH; ≥93.1 mg/mL in DMSO |
| Chemical Name | Angiotensin III (human, mouse) |
| SDF | Download SDF |
| Canonical SMILES | CCC(C)C(C(=O)NC(CC1=CN=CN1)C(=O)N2CCCC2C(=O)NC(CC3=CC=CC=C3)C(=O)O)NC(=O)C(CC4=CC=C(C=C4)O)NC(=O)C(C(C)C)NC(=O)C(CCCN=C(N)N)N |
| 运输条件 | 蓝冰运输或根据您的需求运输。 |
| 一般建议 | 不同厂家不同批次产品溶解度各有差异，仅做参考。若实验所需浓度过大至产品溶解极限，请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存，请尽快用完。 |
质量控制和MSDS
- 批次:
化学结构
