Angiotensin 1/2 (1-9)
mRNA synthesis
In vitro transcription of capped mRNA with modified nucleotides and Poly(A) tail
Tyramide Signal Amplification (TSA)
TSA (Tyramide Signal Amplification), used for signal amplification of ISH, IHC and IC etc.
Phos Binding Reagent Acrylamide
Separation of phosphorylated and non-phosphorylated proteins without phospho-specific antibody
Cell Counting Kit-8 (CCK-8)
A convenient and sensitive way for cell proliferation assay and cytotoxicity assay
SYBR Safe DNA Gel Stain
Safe and sensitive stain for visualization of DNA or RNA in agarose or acrylamide gels.
Inhibitor Cocktails
Protect the integrity of proteins from multiple proteases and phosphatases for different applications.
Angiotensin 1/2(1 - 9)是9个氨基酸的肽段(ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS)。
Angiotensin 1是由肾素作用在肾素血管紧张肽原上形成的,Angiotensin 1具有12个氨基酸,主要由肝脏产生并释放到血液中的α-2-球蛋白。肾素剪切血管紧张肽原上亮氨酸和缬氨酸之间的肽键,产生10个氨基酸肽(Angiotensin 1)。Angiotensin 1主要通过肺内的ACE酶删除两个C端的残基转换为Angiotensin 2(AII)。
Angiotensin是一种多肽激素,可以导致血管收缩以及随后的血压增加。Angiotensin还刺激醛固酮的释放,促进远端肾的钠存留引起血压上升。
Figure1 Formula of Angiotensin I/II (1-9)
参考文献:
1. Basso N, Terragno NA (December 2001). "History about the discovery of the renin-angiotensin system". Hypertension 38 (6): 1246–9.
2. Richard A. Preston. et. (1998). “Age-Race Subgroup Compared With Renin Profile as Predictors of Blood Pressure Response to Antihypertensive Therapy”. JAMA. 1998;280(13):1168-1172.
3. Williams GH, Dluhy RG (2008). "Chapter 336: Disorders of the Adrenal Cortex". In Loscalzo J, Fauci AS, Braunwald E, Kasper DL, Hauser SL, Longo DL. Harrison's principles of internal medicine. McGraw-Hill Medical.
Physical Appearance | A solid |
Storage | Store at -20°C |
M.Wt | 1183.32 |
Cas No. | 34273-12-6 |
Formula | C56H78N16O13 |
Synonyms | H2N-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-OH |
Solubility | ≥118.3 mg/mL in DMSO; insoluble in EtOH; ≥51 mg/mL in H2O |
Chemical Name | Angiotensin 1/2 (1-9) |
SDF | Download SDF |
Canonical SMILES | CCC(C)C(C(=O)NC(CC1=CN=CN1)C(=O)N2CCCC2C(=O)NC(CC3=CC=CC=C3)C(=O)NC(CC4=CN=CN4)C(=O)O)NC(=O)C(CC5=CC=C(C=C5)O)NC(=O)C(C(C)C)NC(=O)C(CCCN=C(N)N)NC(=O)C(CC(=O)O)N |
运输条件 | 蓝冰运输或根据您的需求运输。 |
一般建议 | 不同厂家不同批次产品溶解度各有差异,仅做参考。若实验所需浓度过大至产品溶解极限,请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存,请尽快用完。 |
质量控制和MSDS
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